Weimer / Slupsky | Metabolomics in Food and Nutrition | Buch | 978-1-84569-512-5 | sack.de

Buch, Englisch, 264 Seiten, Format (B × H): 156 mm x 234 mm, Gewicht: 544 g

Weimer / Slupsky

Metabolomics in Food and Nutrition


Erscheinungsjahr 2013
ISBN: 978-1-84569-512-5
Verlag: Elsevier Science & Technology

Buch, Englisch, 264 Seiten, Format (B × H): 156 mm x 234 mm, Gewicht: 544 g

ISBN: 978-1-84569-512-5
Verlag: Elsevier Science & Technology


Metabolomics enables valuable information about the biochemical composition of foods to be rapidly obtained. Since the biochemical profile of food largely determines key food properties such as flavour and shelf life, the information gained using metabolomics-based methods will enable greater control of food quality and also help to determine the relationship between diet and health. Metabolomics in food and nutrition provides an overview of their current and potential use in the food industry.

Part one reviews equipment, methods and data interpretation in metabolomics including the use of nuclear magnetic resonance (NMR), statistical methods in metabolomics, and metabolic reconstruction databases and their application to metabolomics research. Part two explores applications of metabolomics in humans, plants and food. Chapters discuss metabolomics in nutrition, human samples for health assessments, and current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications. Further chapters highlight metabolomic analysis of plants and crops, metabolomics for the safety assessment of genetically modified (GM) crops, and applications of metabolomics in food science including food composition and quality, sensory and nutritional attributes.

With its distinguished editors and team of expert contributors, Metabolomics in food and nutrition is a technical resource for industrial researchers in the food and nutrition sectors interested in the potential of metabolomics methods and academics and postgraduate students working in the area.

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Woodhead Publishing Series in Food Science, Technology and Nutrition

Introduction

Part I: Equipment, methods and data interpretation in metabolomics

Chapter 1: Equipment and metabolite identification (ID) strategies for mass-based metabolomic analysis

Abstract:

1.1 Introduction

1.2 Liquid chromatography

1.3 Gas chromatography

1.4 Mass spectrometry technologies

1.5 Analytical systems

1.6 Compound identification (ID) approaches

1.7 Databases for tracking and interconnections

1.8 Future trends

1.9 Sources of further information and advice

1.10 Acknowledgments

1.11 References

Chapter 2: Metabolomics using nuclear magnetic resonance (NMR)

Abstract:

2.1 Introduction

2.2 Experimental design and preparation

2.3 Experimental process and analysis

2.4 Current applications and future trends

2.5 References

2.6 Appendix: abbreviations

Chapter 3: Statistical methods in metabolomics

Abstract:

3.1 Introduction

3.2 Exploratory/visual approaches

3.3 Inferential approaches

3.4 Multiple hypothesis testing

3.5 Ensemble learning approaches

3.6 Conclusion

3.7 References

3.8 Appendix: software packages used

Chapter 4: Metabolic reconstruction databases and their application to metabolomics research

Abstract:

4.1 Introduction

4.2 Overview of Pathway/Genome Database (PGDB) construction

4.3 Querying PGDBs

4.4 Metabolomics applications

4.5 Sources of further information and advice

4.6 Conclusion

4.7 Acknowledgments

4.8 References

Part II: Applications of metabolomics in humans, plants and food

Chapter 5: Human samples for health assessments

Abstract:

5.1 Introduction

5.2 Sample collections and biobanks

5.3 Variation in metabolite profiles of human biofluids and tissues

5.4 Standards for metabolomic studies

5.5 Conclusions and future trends

5.6 References

Chapter 6: Metabolomics in nutrition

Abstract:

6.1 Introduction

6.2 Epidemiological studies and biomarkers of food intake

6.3 Diet and metabolic syndrome

6.4 The role of intestinal microbiota in nutrition

6.5 Perspectives in nutrition research

6.6 Future trends

6.7 References

Chapter 7: Current methods for the analysis of human milk oligosaccharides (HMOs) and their novel applications

Abstract:

7.1 Introduction

7.2 Analysis of human milk oligosaccharides (HMOs)

7.3 Applications of HMO analysis

7.4 Conclusion

7.5 References

Chapter 8: Metabolomic analysis of plants and crops

Abstract:

8.1 Introduction

8.2 Metabolomic studies on selected Poaceae species

8.3 Metabolomic studies on selected Solanaceae species

8.4 Metabolomic studies on selected Fabaceae species

8.5 Metabolomic studies on selected Brassicaceae and Lamiaceae species

8.6 Plant/crop metabolome databases

8.7 Future trends

8.8 References

Chapter 9: Metabolomics for the safety assessment of genetically modified (GM) crops

Abstract:

9.1 Introduction

9.2 Solanaceous crops

9.3 Cereal crops

9.4 Other crops

9.5 Metabolomics as part of a regulatory risk assessment procedure for the development and evaluation of genetically modified (GM) crops

9.6 Metabolomics and GM food safety: future trends

9.7 Acknowledgements

9.8 References

Chapter 10: Applications of metabolomics in food science: food composition and quality, sensory and nutritional attributes

Abstract:

10.1 Introduction

10.2 Metabolomics for compound identification: authentication and pathogen detection

10.3 Metabolomics for predicting sensory attributes

10.4 Metabolomics and food processing and safety

10.5 Conclusion

10.6 References

Index


Slupsky, Carolyn
Carolyn M. Slupsky is an Associate Professor and Nutritionist at the Foods For Health Institute, University of California, Davis, USA.



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