Buch, Englisch, Band 373, 132 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 3376 g
Buch, Englisch, Band 373, 132 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 3376 g
Reihe: Current Topics in Microbiology and Immunology
ISBN: 978-3-642-40251-7
Verlag: Springer
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Physiologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
Weitere Infos & Material
Development and Function of Cortical Thymic Epithelial Cells.- Mechanisms of Thymus Medulla Development And Function.- Self-peptides in TCR Repertoire Selection and Peripheral T Cell Function.- Central Tolerance Induction.- Trafficking to the Thymus.- The CD4/CD8 Lineages: Central Decisions and Peripheral Modifications for T Lymphocytes.
