Buch, Englisch, 192 Seiten, Format (B × H): 175 mm x 250 mm, Gewicht: 556 g
Buch, Englisch, 192 Seiten, Format (B × H): 175 mm x 250 mm, Gewicht: 556 g
Reihe: Progress in Inflammation Research
ISBN: 978-3-7643-8295-7
Verlag: Springer
This volume gives an overview on the progress in immune synapse research, from basic science to clinical trials, and the major mechanisms involved. It discusses how interfering with T cell activation may lead to immune tolerance, immune modulation, and the recruitment of regulatory T cells; the role of monoclonal antibodies in tolerance induction; and mechanisms maintaining dominant tolerance.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Infektionskrankheiten
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Allergologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
- Naturwissenschaften Biowissenschaften Molekularbiologie
Weitere Infos & Material
The immune synapse and T cell activation: regulation by chemokines.- The induction of regulatory T cells by targeting the immune synapse.- Infiltrating the immunological synapse: prospects for the use of altered peptide ligands for the treatment of immune pathology.- Targeting CD4 for the induction of dominant tolerance.- Anti-CD3: from T cell depletion to tolerance induction.- Immune modulation by CD40L blockade.- CTLA-4-immunoglobulin and indoleamine 2,3-dioxygenase in dominant tolerance.- Adhesion molecules as therapeutic targets.- E3 ubiquitin ligases and immune tolerance: Targeting the immune synapse from within?.- FOXP3 biochemistry will lead to novel drug approaches for vaccines and diseases that lack suppressor T cells.- Transforming growth factor-?: From its effect in T cell activation to a role in dominant tolerance.- From mice to men: the challenges of developing tolerance-inducing biological drugs for the clinic.
