Zeineldin Cancer Nanotechnology

Methods and Protocols
1. Auflage 2017
ISBN: 978-1-4939-6646-2
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 1530, 414 Seiten, eBook

Reihe: Methods in Molecular Biology

This detailed volume presents protocols for advancing the utility of nanotechnology in cancer research toward improving our understanding of cancer biology, prevention, diagnosis, and therapy. There are continuous new discoveries in the field of nanotechnology, thus creating new imaging systems or therapies, and this book focuses on how to employ certain discoveries for studying cancer by presenting principles along with techniques to allow for the transformation of any new discoveries in the field into cancer-studying tools with the hope of bringing in the involvement of biomedical scientists who can enhance the speed of discoveries toward cancer diagnosis and therapy. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and motivating, Cancer Nanotechnology: Methods and Protocols serves as an ideal resource for biomedical scientists interested in the potential of this field as well as for physical scientists and engineers interested in employing nanotechnology in cancer diagnosis and therapy.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Zeineldin, Reema

Inhaltsverzeichnis

Part I: Overviews

1. Cancer Nanotechnology: Opportunities for Prevention, Diagnosis, and Therapy Reema Zeineldin and Joan Syoufjy

2. Improved Targeting of Cancers with Nanotherapeutics Christian Foster, Andre Watson, Joseph Kaplinsky, and Nazila Kamaly

Part II: Nanotechnology-Based Platforms

3. Multifunctional Liposomes Bhawani Aryasomayajula, Giuseppina Salzano, and Vladimir P. Torchilin

4. Multifunctional Concentric FRET-Quantum Dot Probes for Tracking and Imaging of Proteolytic Activity Melissa Massey, Jia Jun Li, and W. Russ Algar

5. Preparation and Characterization of Magnetic Nano-in-Microparticles for Pulmonary Delivery Amber A. McBride, Dominique N. Price, and Pavan Muttil

6. Multifunctionalization of Gold Nanoshells Sandra W. Bishnoi and Yujen Lin

7. Fabrication of Photothermal Stable Gold Nanosphere/Mesoporous Silica Hybrid Nanoparticle Responsive to Near-Infrared Light Bei Cheng and Peisheng Xu

8. Engineering Well-Characterized PEG-Coated Nanoparticles for Elucidating Biological Barriers to Drug Delivery Qi Yang and Samuel K. Lai

9. Piloting Your Nanovehicle to Overcome Biological Barriers Steven M. Richards and Robert B. Campbell

10. Detecting Sonolysis of Polyethylene Glycol Upon Functionalizing Carbon Nanotubes Ruhung Wang, Vasanth S. Murali, and Rockford Draper

11. Methods for Generation and Detection of Non-Stationary Vapor Nanobubbles Around Plasmonic Nanoparticles Ekaterina Y. Lukianova-Hleb and Dmitri O. Lapotko

Part III: Nanotechnology to Study Cancer

12. Force Measurements for Cancer Cells Vivek Rajasekharan, Varun K.A. Sreenivasan, and Brenda Farrell

13. Fractal Analysis of Cancer Cell Surface Igor Sokolov and Maxim E. Dokukin

14. Quantitative Evaluation of the Enhanced Permeability and Retention (EPR) Effect Luisa M. Russell, Charlene M. Dawidczyk, and Peter C. Searson

Part IV: Nanotechnology for Prevention and Detection/Imaging of Cancer

15. Nanotechnology-Based Cancer Vaccines Aws Alshamsan

16. Designing Multicomponent Nanosystems for Rapid Detection of Circulating Tumor Cells Shashwat S. Banerjee, Vrushali Khobragade, and Jayant Khandare

17. Fluorescence and Bioluminescence Imaging of Orthotopic Brain Tumors in Mice Emilie McKinnon, Alfred Moore, Suraj Dixit, Yun Zhu, and Ann-Marie Broome

18. An Ultrasensitive Biosensing Platform Employing Acetylcholinesterase and Gold Nanoparticles Dingbin Liu and Xiaoyuan Chen

Part V: Nanotechnology-Based Therapies

19. Gene Silencing Using Multifunctionalized Gold Nanoparticles for Cancer Therapy Alexandra R. Fernandes and Pedro V. Baptista

20. Generation of Dose Response Curves and Improved IC50’s for PARP Inhibitor Nanoformulations Paige Baldwin, Shifalika Tangutoori, and Srinivas Sridhar

21. Artificial Antigen-Presenting Cells for Immunotherapies Alyssa L. Siefert, Tarek M. Fahmy, and Dongin Kim

22. Exploiting Uptake of Nanoparticles by Phagocytes for Cancer Treatment< Mee Rie Sheen and Steven Fiering

23. Pulmonary Delivery of Magnetically-Targeted Nano-in-Microparticles Amber A. McBride, Dominique N. Price, and Pavan Muttil

24. Neutron-Activatable Nanoparticles for Intraperitoneal Radiation Therapy Derek Hargrove and Xiuling Lu

25. Nanoparticle-Mediated X-Ray Radiation Enhancement for Cancer Therapy Autumn D. Paro, Ilanchezhian Shanmugam, and Anne L. van de Ven

26. Radiosensitizing Silica Nanoparticles Encapsulating Docetaxel for Treatment of Prostate Cancer Jodi Belz, Noelle Castilla-Ojo, Srinivas Sridhar, and Rajiv Kumar