You / Morris Drug Transporters

Molecular Characterization and Role in Drug Disposition
2. Auflage 2014
ISBN: 978-1-118-70504-9
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 528 Seiten, E-Book

Reihe: Wiley series in drug discovery and development

This new edition overviews drug transporters and presents theprinciples of drug transport and associated techniques, featuringnew chapters on multidrug and toxin extrusion proteins, placentaltransport, in silico approaches in drug discovery, andregulatory guidance for drug transport studies in drugdevelopment.
* Describes drug transporter families, mechanisms,and clinical implications along with experimental methods forstudying and characterizing drug transporters
* Includes new chapters on multidrug and toxin extrusionproteins, placental transport and in silico approaches in drugdiscovery
* Has a new chapter covering regulatory guidance for theevaluation of drug transport in drug development with globalcriteria used for drug transporters in clinical trials
* Arranges material to go from fundamental mechanisms toclinical outcomes, making the book useful for novice and expertreaders

Autoren/Hrsg.

You, Guofeng

Morris, Marilyn E.

Weitere Mitwirkende

Wang, Binghe

Über Autor(innen)

Guofeng You is a Distinguished Professor of Pharmaceuticsin the Ernest Mario School of Pharmacy at Rutgers University, USA.She has published numerous original research articles in the fieldof drug transport. She has been serving on several grant reviewpanels of the National Institutes of Health and is on the editorialboards of leading journals. She was the coeditor for the firstedition of this book (Wiley, 2007).
Marilyn E. Morris is Professor in the Department ofPharmaceutical Sciences at the University at Buffalo, StateUniversity of New York. She is a Fellow of the American Associationof Pharmaceutical Scientists (AAPS) and the American Associationfor the Advancement of Science (AAAS). and currently serves on theeditorial boards of leading journals and was also co-editor for thefirst edition of this book (Wiley, 2007).