Wiseman / Haynes Coordinating Organismal Physiology Through the Unfolded Protein Response

1. Auflage 2018
ISBN: 978-3-319-78530-1
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 414, 213 Seiten, eBook

Reihe: Current Topics in Microbiology and Immunology

This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike.

Zielgruppe

Research

Autoren/Hrsg.

Wiseman, R. Luke

Haynes, Cole M.

Inhaltsverzeichnis

Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response.- Cell Non-Autonomous UPR
ER
Signaling.- The unfolded protein response in the immune cell development: Putting the caretaker in the driving seat.- Mitochondria associated membranes and ER stress.- Coordinating Organismal Metabolism during Protein Misfolding in the ER Through the Unfolded Protein Response.- ER stress and neurodegenerative disease: a cause or effect relationship?- Driving cancer tumorigenesis and metastasis through UPR signaling.- ER Protein Quality Control and the Unfolded Protein Response in the Heart.

Über Autor(innen)

R. Luke Wiseman
Associate ProfessorDepartment of Molecular MedicineThe Scripps Research Institute MEM 220
La Jolla, CA 92037, USA
Phone: [phone]
Email: [e-mail]
Cole M. HaynesAssociate ProfessorUniversity of Massachusetts Medical SchoolWorcester, MA 01605, USAEmail:[e-mail]