Wilkins / Lay Identification of Microorganisms by Mass Spectrometry

1. Auflage 2005
ISBN: 978-0-471-74863-2
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 352 Seiten, E-Book

Reihe: Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications

A multidisciplinary approach to understanding the fundamentals ofmass spectrometry for bacterial analysis
From chemotaxonomy to characterization of targeted proteins,Identification of Microorganisms by Mass Spectrometry provides anoverview of both well-established and cutting-edge massspectrometry techniques for identifying microorganisms. A vitaltool for microbiologists, health professionals, and analyticalchemists, the text is designed to help scientists select the mosteffective techniques for use in biomedical, biochemical,pharmaceutical, and bioterror defense applications.
Since microbiological applications of mass spectrometry require abasic understanding of both microbiology and analytical chemistry,the editors have incorporated material from both disciplines sothat readers from either field will come to understand thenecessary principles of the other. Featuring contributions fromsome of the most recognized experts in both fields, this volumeprovides specific examples of fundamental methods as well asapproaches developed in the last decade, including:
* Metastable atom bombardment pyrolysis mass spectrometry
* Matrix-assisted laser desorption/ionization mass spectrometry(MALDI)
* MALDI time-of-flight mass spectrometry (MALDI-TOF MS) of intactbacteria
* High-resolution Fourier transform mass spectrometry (FTMS)
* Electrospray ionization (ESI) mass spectrometry
Identification of Microorganisms by Mass Spectrometry representsthe most comprehensive and up-to-date work on the topic currentlyavailable. It is liberally illustrated with figures and tables andcovers every aspect of spectrometric identification ofmicroorganisms, including experimental procedures, various means ofsample preparation, data analysis, and interpretation of complexmass spectral data.

Autoren/Hrsg.

Wilkins, Charles L.

Lay, Jackson O.

Über Autor(innen)

CHARLES L. WILKINS, PhD, is a Distinguished Professor in theDepartment of Chemistry and Biochemistry at the University ofArkansas. He is the author or coauthor of over 250 scientificpublications and has received numerous awards for his research.
JACKSON O. LAY, Jr., PhD, is the Director of the ArkansasStatewide Mass Spectrometry Facility at the University of Arkansas,and the author or coauthor of more than 100 publications in thefield. In addition to his work with bacteria, he has developed massspectrometry methods for cancer research and toxicology.