Wang / Boons Carbohydrate Recognition

Biological Problems, Methods, and Applications
1. Auflage 2011
ISBN: 978-1-118-01757-9
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 440 Seiten, E-Book

Reihe: Wiley series in drug discovery and development

This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.

Autoren/Hrsg.

Wang, Binghe

Boons, Geert-Jan

Inhaltsverzeichnis

PREFACE.
CONTRIBUTORS.
1 MAMMALIAN GLYCAN BIOSYNTHESIS: BUILDING A TEMPLATE FORBIOLOGICAL RECOGNITION (M. Adam Meledeo, Venkata D. P.Paruchuri, Jian Du, Zhiyun Wang, and Kevin J. Yarema).
2 THE ROLES OF CARBOHYDRATE BINDING IN CELL ADHESION ANDINFLAMMATION (Ken Kitajima and Chihiro Sato).
3 THE ROLE OF CARBOHYDRATES IN VIRAL INFECTIONS (Gillian M.Air).
4 THE ROLE OF CARBOHYDRATES IN BACTERIAL INFECTIONS (RolandJ. Pieters).
5 THE ROLES OF CARBOHYDRATE BINDING IN FERTILIZATION (DavidJ. Miller).
6 CARBOHYDRATE BIOMARKERS (Yunfeng Cheng, Nanting Ni, HanjingPeng, Shan Jin, and Binghe Wang).
7 GALECTINS AND THEIR ROLE IN VARIOUS BIOLOGICAL PROCESSES(Sarika Saraswati, Ashley Stanley Block, and Alan B.Diekman).
8 GLYCOIMMUNOLOGY (Ani Grigorian and Barbara Newton).
9 TOOLS FOR GLYCOMICS: GLYCAN AND LECTIN MICROARRAYS (JeffGildersleeve).
10 COMBINATORIAL BIOSYNTHESIS OF COMPLEX CARBOHYDRATES (HaiYu and Xi Chen).
11 MASS SPECTROMETRY IN CARBOHYDRATE SEQUENCING AND BINDINGANALYSIS (Gregory O. Staples and Joseph Zaia).
12 SYNTHETIC LECTIN MIMICS ARTIFICIAL CARBOHYDRATE RECEPTORS(Xiaochuan Yang, Yunfeng (Jerry) Cheng, and BingheWang).
13 LECTIN BINDING AND ITS STRUCTURAL BASIS (Annabelle Varrot,Bertrand Blanchard, and Anne Imberty).
14 MULTIVALENCY IN CARBOHYDRATE BINDING (Mark L. Wolfendenand Mary J. Cloninger).
15 CARBOHYDRATE BINDING AGENTS: POTENTIAL THERAPEUTICS WITHMULTIPLE INHIBITORY ACTIONS AGAINST ENVELOPED VIRUSES (K.O.Francois and J. Balzarini).
16 INFORMATICS FOR GLYCOBIOLOGY AND GLYCOMICS (Kiyoko F.Aoki-Kinoshita).
INDEX.

Über Autor(innen)

BINGHE WANG, PhD, is Professor and Chair of the Departmentof Chemistry at Georgia State University as well as GeorgiaResearch Alliance Eminent Scholar in Drug Discovery. He isEditor-in-Chief of the journal Medicinal Research Reviews, SeriesEditor for the Wiley Series in Drug Discovery and Development, andeditor of Drug Delivery: Principles and Applications andChemosensors: Principles, Strategies, and Applications (Wiley).
GEERT-JAN BOONS, PhD, is Franklin Professor of Chemistryand Professor in the Complex Carbohydrate Research Center at theUniversity of Georgia. He is on the editorial boards of severaljournals on carbohydrates, including European Journal of Chemistryand Journal of Carbohydrate Chemistry, and is also coeditor ofCarbohydrate-Based Immunotherapies and Vaccines (Wiley).