Organoids for Personalised Cancer Medicine

A Vision Assessment of an Emerging Health Technology
Erscheinungsjahr 2025
ISBN: 978-3-031-85534-4
Verlag: Springer

Buch, Englisch, 126 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 219 g

Reihe: SpringerBriefs in Philosophy

This open access book builds on and updates work performed in the HYBRIDA project, funded by the EU to develop an ethical framework for organoid research. Organoids are three-dimensional stem cell constructs that mimic organs of the body or tumours. Patient-derived organoids are envisioned to be grown from individual patients’ tumours and used to tailor the most effective and safest treatments in a new form of personalized medicine.  This text offers a critical assessment of this vision from the perspective of philosophy of medicine. The authors present a tailored “vision assessment”, presented as examples of methodological development, and applied to objects. They first analyse and describe the vision of using organoids for personalized cancer medicine, then critically evaluate this vision and finally comment on ethical implications of the epistemological issues and how to handle them. The authors further draw on sources for empirical inquiries. This book presents an exercise in health technology assessment conducted by philosophers. Its core readership are philosophers of medicine and bioethicists interested in personalized medicine and stem cell research.

Zielgruppe

Research

Autoren/Hrsg.

Vogt, Henrik

Gaillard, Maxence

Green, Sara

Fachgebiete

• Geisteswissenschaften Philosophie Angewandte Ethik & Soziale Verantwortung Medizinische Ethik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizinische Ethik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien

Inhaltsverzeichnis

Introduction.- Methodological development.- Vision analysis of patient-derived organoids for personalized cancer medicine.- Vision evaluation of patient-derived organoids in the clinic.- Conclusion.

Über Autor(innen)

Henrik Vogt and Maxence Gaillard both work at the Center for Medical Ethics, University of Oslo, Norway.

Sara Green is affiliated with the Department of Science Education, University of Copenhagen, Denmark. She is an Associate Professor at the Section for History and Philosophy of Science.