Buch, Englisch, 247 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 400 g
Reihe: Topics in Current Chemistry
Aromatic Polyketides, Isoprenoids, Alkaloids
Buch, Englisch, 247 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 400 g
Reihe: Topics in Current Chemistry
ISBN: 978-3-642-08583-3
Verlag: Springer
This book is the second of two volumes that deal with discovery of chemical pathways of biosynthesis of natural products (secondary metabolites). The first volume covered the use of isotopes in biosynthetic research and the formation of enzyme cofactors and reduced polyketides. This second volume describes biosynthesis of aromatic (unreduced) polyketides, enzymes responsible for cyclization of terpenoids (isoprenoids), and biochemical generation of selected classes of alkaloids (prenylated tryptophan, tropane, pyrrolizidine). Knowledge of the pathways and the techniques to elucidate them opens the door to combinatorial biosynthesis as well as to the production of targeted pharmaceutical agents utilizing a combination of chemistry, molecular biology and protein biochemistry.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
- Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Industrielle Biotechnologie
- Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
Weitere Infos & Material
Biosynthesis of Aromatic Polyketides.- Cyclization Enzymes in the Biosynthesis of Monoterpenes, Sesquiterpenes, and Diterpenes.- Biosynthesis of Prenylated Alkaloids Derived from Tryptophan.- Tropane and Related Alkaloids.- Biosynthesis and Metabolism of Pyrrolizidine Alkaloids in Plants and Specialized Insect Herbivores.