Alkenations, Cross Couplings, Insertions, Substitutions, and Halomethylations
E-Book, Englisch, 558 Seiten, PDF, Format (B × H): 170 mm x 240 mm
ISBN: 978-3-13-176541-3
Verlag: Thieme
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
Synthesis critically reviews the state of the art of a wide variety of reactions
by which one carbon atom is added to an organic molecule, forming a C-C bond. In
spite of the numerous classic reactions of this kind, there has been enormous
progress in recent years, especially for those reactions involving catalytic
methods. Introduction of substituted methyl groups is a major challenge and only
very recently the first catalysts have been discovered that enable the
introduction of fluoromethyl groups in aromatics.
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Weitere Infos & Material
2.1 C-1 Alkenation2.1.1 Modern Variants of Wittig, Peterson, and Tebbe Protocols2.2 C—C Cross Coupling2.2.1 Cross-Coupling Methods for Methylation2.2.2 Carbonylation of Aryl and Vinyl Halides2.2.3 Cyanation of Aryl Halides2.2.4 Oxidative Coupling of Nitromethane2.3 Insertion into C—H Bonds2.3.1 Carbene Insertion into C—H Bonds with C-12.4 Insertion into C—O and C—N Bonds2.4.1 Carbon Monoxide Insertion into Epoxides and Oxetanes2.4.2 Carbon Monoxide Insertion into Aziridines2.5 Substitution Reactions2.5.1 Hydroformylation of Epoxides2.5.2 Cyanation of Epoxides2.5.3 Cyanation of Aziridines2.5.4 Carboxylation of Organometallic Reagents2.5.5 Reaction of Formaldehyde with Organometallic Reagents2.5.6 Mannich-Type Reactions2.5.7 Formylation and the Vilsmeier Reagent2.5.8 Metathesis Adding a C-1 Unit2.6 Halomethylation2.6.1 Trifluoromethylation2.6.2 Difluoro- and Fluoromethylation2.6.3 Karasch Reaction (Atom-Transfer Radical Addition Reactions)
