The Pneumococcus

Neuausgabe 2004
ISBN: 978-1-55581-297-3
Verlag: Wiley

Buch, Englisch, 427 Seiten, Format (B × H): 176 mm x 261 mm, Gewicht: 1116 g

A state-of-the-art examination of research in this field and the impact of this gram-positive pathogen on human disease. • Provides coverage of topics in basic microbiology such as details of DNA transformation, molecular and medical epidemiology, the molecular basis of invasive disease, and various interactions with host defenses. • Presents important historical information on the field of pneumococcal research and suggests strategies for future investigation. • Serves as a valuable source of information for graduate and medical school students, infectious disease specialists, and field researchers in the pathogenesis of gram-positive bacteria.

This title is published by the American Society for Microbiology Press and distributed by Taylor and Francis in rest of world territories.

Autoren/Hrsg.

Tuomanen, Elaine I

Tuomanen, Elaine I.

Mitchell, Timothy J.

Morrison, Donald

Fachgebiete

• Naturwissenschaften Biowissenschaften Mikrobiologie

Inhaltsverzeichnis

Table of Contents

The Bacteria

1. What is a Pneumococcus? Christopher G. Dowson

2. Comparative Genomics of S. pneumoniae: Intra-Strain Diversity and Genome Plasticity, Hervé Tettelin and Susan Hollingshead

3. Capsule, Janet Yother

4. Choline-Binding Proteins, Edwin Swiatlo, Larry S. McDaniel, and David E. Briles

5. Pneumolysin and Other Virulence Proteins, Tim J. Mitchell

6. Cell Wall Hydrolases, Rubens Lopez, Ernesto Garcia, Pedro Garcia, and José Luis Garcia

7. Transformation, Sanford A. Lacks

Host-Microbe Interactions

8. Evolutionary and Population Biology of Streptococcus pneumoniae, Brian G. Spratt, William P. Hanage, and Angela B. Brueggemann

9. Pneumococcal Carriage, Derrick W. Crook, Angela B. Brueggemann, Karen Sleeman, and Timothy E. A. Peto

10. Epidemiology of Pneumococcal Disease, Jay C. Butler

11. Mechanisms of Carriage, Jeffrey N. Weiser

Invasion and Infection

12. Inflammation and Host Defense, Paul Anthony Majcherczyk and Philippe Moreillon

13. Interactions of Streptococcus pneumoniae with the Proteins of the Complement Pathways, Margaret K. Hostetter

14. A Pathogenic Categorization of Clinical Syndromes Caused by Streptococcus pneumoniae, Daniel M. Musher

15. Attachment and Invasion of the Respiratory Tract, Elaine I. Tuomanen

16. Pathogenesis of Pneumococcal Meningitis, Joerg R. Weber

17. Immunodeficiency and Invasive Pneumococcal Disease, Edward N. Janoff and Jeffrey B. Rubins

Treatment and Prevention

18. Changing the Ecology of Pneumococci with Antibiotics and Vaccines, Ron Dagan and Marc Lipsitch

19. Pneumococcal Infections: Therapeutic Strategies and Pitfalls, Kathryn M. Edwards

20. Clinical Relevance of Antibiotic Resistance in Pneumococcal Infections, Keith P. Klugman

21. Mechanisms for Penicillin Resistance in Streptococcus pneumoniae: Penicillin Binding Proteins, Gene Transfer, and Cell Wall Metabolism, Carina Bergmann, Fang Chi, Shwan Rachid and Regine Hakenbeck

22. Macrolide, Quinolone, and Other Non-ß-Lactam Antibiotic Resistance in Streptococcus pneumoniae, Karita Ambrose and David S. Stephens

23. The Humoral Immune Response to Streptococcus pneumoniae, Clifford M. Snapper, Jesus Colino, Abdul Q. Khan and Zheng Qi Wu

24. New Pneumococcal Vaccines: Basic Science Developments, James C. Paton

25. Vaccine-Induced Immunity, H. Käyhty and H. Mäkelä