Medications for Older Persons

Recommendations, Harms, Evidence
Erscheinungsjahr 2025
ISBN: 978-0-443-29025-1
Verlag: Elsevier Science

Buch, Englisch, 356 Seiten, Format (B × H): 190 mm x 240 mm, Gewicht: 794 g

Medications for Older Persons: Recommendations, Harms, Evidence provides a comprehensive resource detailing the benefits of medications for older individuals. It also addresses the potential harms associated with the prescription of potentially inappropriate medications or omissions in prescribing and examines how many adverse events, rehospitalizations, and deaths can be attributed to these medications. The book opens with a summary of medications that most benefit older patients, followed by the impact of older persons’ alcohol consumption, self-medication, and medication list accuracy and how these factors correlate to health outcomes.

The remainder of the book is devoted to the assessment of medication groups focusing on Numbers Needed to Treat, Numbers Needed to Harm, and characteristics and numbers of adverse events. Medication groups covered include cardiovascular, central nervous system, renal, gastrointestinal, musculoskeletal, respiratory, endocrine, pain, and fall prevention.

Autoren/Hrsg.

Thomas, Roger

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften

Inhaltsverzeichnis

Section 1. Recommendations for medications of older persons

1. A summary of medications that most benefit older patients: for clinicians, patients, their families, policy makers and health ministries

2. STOPP and American Geriatrics Society “potentially inappropriate medications" (PIMs) and START ”potential prescribing omissions” (PPOs)

3. The Calgary study of 295,706 admissions of older persons to four acute care hospitals 2013-2021

4. Adverse drug interactions in the Veterans Affairs Adverse Drug Event Reporting System

5. Pharmacokinetics and pharmacodynamics in older persons

6. Methods to identify adverse drug interactions and effects

7. How personalized medicine has changed senior patient outcomes at the Mayo Clinic and other centers

Section 2. Older persons alcohol consumption, self-medication, and medication list accuracy

8. Older persons alcohol consumption

9. Self-medication and over the counter medications by older persons

10. The accuracy of recording medication lists, transferring lists between community practitioners and medical institutions, and the potential effects on the accuracy of assessing PIMs, PPOs and adverse medication events

Section 3. Cardiovascular medications

11. Medications for hypertension

12. Medications for heart failure

13. Medications for arrhythmias

14. Medications for diuresis

15. Medications for coagulation

Section 4. Central Nervous System medications

16. Medications for depression

17. Medications for anxiety

18. Medications for insomnia

19. Neuroleptic/antipsychotic medications

20. Avoiding medications with risks of delirium

21. Avoiding medications that augment dementia

Section 5. Renal medication

22. Prescribing to reduce risks of renal insufficiency and failure

Section 6. Gastrointestinal medications

23. Prescribing to reduce the risks of peptic ulcer disease, gastritis, and esophagitis and treat if present

24. Prescribing to reduce the risks of constipation or diarrhea

Section 7. Musculoskeletal medications

25. Medications for arthritis

26. Medications for osteoporosis

Section 8. Respiratory medications

27. Medications for COPD

Section 9. Endocrine medications

28. Medications for diabetes

Section 10. Pain medications

29. Non-opioid analgesics and opioids for seniors

Section 11. Changing prescribing to prevent falls

30. Prescribing to prevent falls

Über Autor(innen)

Thomas, Roger
Roger E. Thomas, MD, PhD, CCFP, FCFP, MRCGP, holds a BA Honors in Economics from Cambridge, PhD in Sociology from Yale, an MD from McMaster, and practiced as a rural physician 1979 in Newfoundland. Through 1980 to 1983, Dr. Thomas performed Medical Missionary work in Malawi. Through his career, Dr. Thomas has held faculty positions at East Carolina University, Toronto, Ottawa, Newfoundland, and currently is an Emeritus Professor of Family Medicine at the University of Calgary. He has 187 peer-reviewed publications and 108 abstracts on such topics as adverse medication events on seniors' rehospitalization and death, prescribing for seniors using genomic data, evidence-based methods of deprescribing to reduce readmissions and death, total costs of seniors' care and options to finance most needed care.