Technau Brain Development in Drosophila melanogaster

1. Auflage 2009
ISBN: 978-0-387-78261-4
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 628, 160 Seiten, eBook

Reihe: Advances in Experimental Medicine and Biology

The fruitfly Drosophila melanogaster is an ideal model system to study processes of the central nervous system This book provides an overview of some major facets of recent research on Drosophila brain development.

Zielgruppe

Research

Autoren/Hrsg.

Technau, Gerhard Martin

Inhaltsverzeichnis

CONTENTS1. The Development of the Drosophila Larval Brain........... 1Volker Hartenstein, Shana Spindler, Wayne Pereanu and Siaumin FungAbstract................................................................................................................................. 1Synopsis of the Phases and Elements of Drosophila Brain Development........................ 1Progenitors of the Drosophila Brain: Neuroblasts and Ganglion Mother Cells............. 3The Generic Cell Types of the Drosophila Brain................................................................ 8Neuroanatomy of the Developing Drosophila Brain: The Systems of Lineages,Tracts and Compartments......................................................................................... 17Outlook............................................................................................................................... 292. Anteroposterior Regionalization of the Brain:Genetic and Comparative Aspects............................................. 32Robert Lichtneckert and Heinrich ReichertAbstract............................................................................................................................... 32Introduction........................................................................................................................ 32The Cephalic Gap Genes Otd/Otx and Ems/Emx Control AnteriorBrain Development..................................................................................................... 34The Hox Genes Pattern the Posterior Brain..................................................................... 36Evidence for a Tripartite Organization of the Brain....................................................... 373. Dorsoventral Paterning of the Brain:A Comparative Approach.................................................................. 42Rolf Urbach and Gerhard M. TechnauAbstract ............................................................................................................................... 42Introduction........................................................................................................................ 42DV Patterning of the Truncal Part of the CNS in Drosophila and vertebrates............ 45DV patterning of the brain in Drosophila........................................................................ 48A comparison with DV regionalization of the vertebrate telencephalon................... 52Conclusions......................................................................................................................... 53xii Contents4. Disection of the Embryonic Brain UsingPhotoactivated Gene Expresion.............................................. 57Jonathan MindenAbstract............................................................................................................................... 57Introduction........................................................................................................................ 57Procephalic Blastoderm Fate Map.................................................................................... 58Brain-Forming Mitotic Domains Populate Distinct Brain Regions............................... 58Conclusion.......................................................................................................................... 675. Design of the Larval Chemosensory System....................... 69Reinhard F. StockerAbstract ............................................................................................................................... 69Introduction........................................................................................................................ 69Chemosensory Organs of the Larval Head...................................................................... 70Olfactory System................................................................................................................. 71Gustatory System................................................................................................................ 77The Drosophila Larva as a Model for Smell and Taste.................................................... 786. Development of the Drosophila Olfactory System...... 82Veronica Rodrigues and Thomas HummelAbstract............................................................................................................................... 82Introduction........................................................................................................................ 82Organization of the Drosophila Adult Olfactory System................................................. 84Specification of the Olfactory Sense Organs.................................................................... 84Olfactory Lineages Revisited............................................................................................. 87Origin of Glial Cells............................................................................................................ 89Development of ORN Connectivity................................................................................... 89Olfactory Map Organization............................................................................................. 90Cellular and Molecular Mechanisms of ORN Wiring Specificity.................................. 91Specification of Projection Neurons.................................................................................. 92Development of PN Dendrites............................................................................................ 95Concluding Remarks.......................................................................................................... 967. The Olfactory Sensory Map in Drosophila.......................... 102Philippe P. Laissue and Leslie B. VosshallAbstract............................................................................................................................. 102Introduction...................................................................................................................... 102Olfactory Organs and Olfactory Sensory Neurons of Drosophila................................ 103Odorant Receptor Gene Expression................................................................................ 104Ligand Tuning Profiles..................................................................................................... 105A Receptor-Based Map of Glomerular Projections....................................................... 108Sexual Dimorphism in the Drosophila Olfactory System...............................................111Concluding Remarks........................................................................................................ 1128. Optic Lobe Development.................................................................115Karl-Friedrich Fischbach and Peter Robin HiesingerAbstract............................................................................................................................. 115Introduction...................................................................................................................... 115The Adult Visual System Is Organized into Parallel VisuotopticFunctional Pathways................................................................................................. 116Lamina Development........................................................................................................ 120Medulla and Lobula Complex Development.................................................................. 126Concluding Remarks........................................................................................................ 1319. Clonal Unit Architecture of the Adult Fly Brain........ 137Kei Ito and Takeshi AwasakiAbstract............................................................................................................................. 137Introduction...................................................................................................................... 137Structure of the Adult Brain............................................................................................ 137Techniques for Visualising Clonally Related Progeny................................................... 139Clonal Unit Architecture in the Adult Brain.................................................................. 147Formation of the Clonal Units During Development..................................................... 150Functional Importance of the Clonal Units.................................................................... 154Conclusion........................................................................................................................ 156INDEX.............................................................................................................................TBA