Buch, Englisch, Band 628, 160 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 580 g
Buch, Englisch, Band 628, 160 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 580 g
Reihe: Advances in Experimental Medicine and Biology
ISBN: 978-0-387-78260-7
Verlag: Springer
betweenDrosophila and mouse.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Wirbellose (Invertebrata) Insekten (Entomologie)
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
- Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Tierphysiologie
Weitere Infos & Material
CONTENTS
1. The Development of the Drosophila Larval Brain........... 1
Volker Hartenstein, Shana Spindler, Wayne Pereanu and Siaumin Fung
Abstract................................................................................................................................. 1
Synopsis of the Phases and Elements of Drosophila Brain Development........................ 1
Progenitors of the Drosophila Brain: Neuroblasts and Ganglion Mother Cells............. 3
The Generic Cell Types of the Drosophila Brain................................................................ 8
Neuroanatomy of the Developing Drosophila Brain: The Systems of Lineages,
Tracts and Compartments......................................................................................... 17
Outlook............................................................................................................................... 29
2. Anteroposterior Regionalization of the Brain:
Genetic and Comparative Aspects............................................. 32
Robert Lichtneckert and Heinrich Reichert
Abstract............................................................................................................................... 32
Introduction........................................................................................................................ 32
The Cephalic Gap Genes Otd/Otx and Ems/Emx Control Anterior
Brain Development..................................................................................................... 34
The Hox Genes Pattern the Posterior Brain..................................................................... 36
Evidence for a Tripartite Organization of the Brain....................................................... 37
3. Dorsoventral Paterning of the Brain:
A Comparative Approach.................................................................. 42
Rolf Urbach and Gerhard M. Technau
Abstract ............................................................................................................................... 42
Introduction........................................................................................................................ 42
DV Patterning of the Truncal Part of the CNS in Drosophila and vertebrates............ 45
DV patterning of the brain in Drosophila........................................................................ 48
A comparison with DV regionalization of the vertebrate telencephalon................... 52
Conclusions......................................................................................................................... 53
xii Contents
4. Disection of the Embryonic Brain Using
Photoactivated Gene Expresion.............................................. 57
Jonathan Minden
Abstract............................................................................................................................... 57
Introduction........................................................................................................................ 57
Procephalic Blastoderm Fate Map.................................................................................... 58
Brain-Forming Mitotic Domains Populate Distinct Brain Regions............................... 58
Conclusion.......................................................................................................................... 67
5. Design of the Larval Chemosensory System....................... 69
Reinhard F. Stocker
Abstract ............................................................................................................................... 69
Introduction........................................................................................................................ 69
Chemosensory Organs of the Larval Head...................................................................... 70
Olfactory System................................................................................................................. 71
Gustatory System................................................................................................................ 77
The Drosophila Larva as a Model for Smell and Taste.................................................... 78
6. Development of the Drosophila Olfactory System...... 82
Veronica Rodrigues and Thomas Hummel
Abstract............................................................................................................................... 82
Introduction........................................................................................................................ 82
Organization of the Drosophila Adult Olfactory System................................................. 84
Specification of the Olfactory Sense Organs.................................................................... 84
Olfactory Lineages Revisited............................................................................................. 87
Origin of Glial Cells............................................................................................................ 89
Development of ORN Connectivity................................................................................... 89
Olfactory Map Organization............................................................................................. 90
Cellular and Molecular Mechanisms of ORN Wiring Specificity.................................. 91
Specification of Projection Neurons.................................................................................. 92
Development of PN Dendrites............................................................................................ 95
Concluding Remarks.......................................................................................................... 96
7. The Olfactory Sensory Map in Drosophila.......................... 102
Philippe P. Laissue and Leslie B. Vosshall
Abstract............................................................................................................................. 102
Introduction...................................................................................................................... 102
Olfactory Organs and Olfactory Sensory Neurons of Drosophila................................ 103
Odorant Receptor Gene Expression................................................................................ 104
Ligand Tuning Profiles..................................................................................................... 105
A Receptor-Based Map of Glomerular Projections....................................................... 108
Sexual Dimorphism in the Drosophila Olfactory System...............................................111
Concluding Remarks........................................................................................................ 112
8. Optic Lobe Development.................................................................115
Karl-Friedrich Fischbach and Peter Robin Hiesinger
Abstract............................................................................................................................. 115
Introduction...................................................................................................................... 115
The Adult Visual System Is Organized into Parallel Visuotoptic
Functional Pathways................................................................................................. 116
Lamina Development........................................................................................................ 120
Medulla and Lobula Complex Development.................................................................. 126
Concluding Remarks........................................................................................................ 131
9. Clonal Unit Architecture of the Adult Fly Brain........ 137
Kei Ito and Takeshi Awasaki
Abstract............................................................................................................................. 137
Introduction...................................................................................................................... 137
Structure of the Adult Brain............................................................................................ 137
Techniques for Visualising Clonally Related Progeny................................................... 139
Clonal Unit Architecture in the Adult Brain.................................................................. 147
Formation of the Clonal Units During Development..................................................... 150
Functional Importance of the Clonal Units.................................................................... 154
Conclusion........................................................................................................................ 156
INDEX.............................................................................................................................TBA
