Handbook of Glycosyltransferases and Related Genes

1. Auflage 2002
ISBN: 978-4-431-70311-2
Verlag: Springer Japan

Buch, Englisch, 670 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 1200 g

This handbook provides comprehensive information on all known glycosyltransferases and their related genes. Nearly 100 chapters, contributed by experts in the field, compile the latest information in a concise format for easy reference. Readers have access to the databases for each glycogene with the accession numbers in each chapter, and maps of biosynthetic pathways of glycoconjugates are also given. The book deals comprehensively with enzymes involved in the biosynthesis of carbohydrate chains of glycoconjugates whose genes have been cloned. Application of gene technology to these enzymes has brought significant progress in glycobiology and glycotechnology in the past decade, making knowledge of the glycogenes that encode glycosyltransferases and related enzymes a shortcut to understanding glycobiology. This handbook is essential for research in functional glycomics, integrating glycobiology and glycotechnology, as it comes of age in the post-genomic era.

Zielgruppe

Research

Autoren/Hrsg.

Taniguchi, Naoyuki

Honke, Koichi

Fukuda, Minoru

Fachgebiete

• Naturwissenschaften Biowissenschaften Zellbiologie
• Naturwissenschaften Chemie Organische Chemie
• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Biochemische Immunologie

Inhaltsverzeichnis

Part 1Glucosyltransferase
1 GlcCer Synthase (UDP-Glucose:Ceramide Glucosyltransferase, UGCG)
Part 2Galactosyltransferases
2 b4-Galactosyltransferase-I
3 b4-Galactosyltransferase-II, -III, -IV, -V, -VI, and -VII
4 b3-Galactosyltransferase-I, -II, and -III
5 b3-Galactosyltransferase-IV (GM1 Synthase)
6 b3-Galactosyltransferase-V
7 a3-Galactosyltransferase
8 GalCer Synthase (Ceramide Galactosyltransferase, CGT)
Part 3N-Acetylglucosaminyltransferases
9 N-Acetylglucosaminyltransferase-I
10 N-Acetylglucosaminyltransferase-II
11 N-Acetylglucosaminyltransferase-III
12 N-Acetylglucosaminyltransferase-IV
13 N-Acetylglucosaminyltransferase-V
14 N-Acetylglucosaminyltransferase-VI
15 b3-N-Acetylglucosaminyltransferase (Fringe)
16 b3-N-Acetylglucosaminyltransferase (iGnT)
17 b6-N-Acetylglucosaminyltransferase (IGnT)
18 Core 2 b6-N-Acetylglucosaminyltransferase-1 and -3
19 Core 2 b6-N-Acetylglucosaminyltransferase-2
20 a4-N-Acetylglucosaminyltransferase
21 O-GlcNAc Transferase
Part 4N-Acetylgalactosaminyltransferases
22 Polypeptide N-Acetylgalactosaminyltransferases
23 b4-N-Acetylgalactosaminyltransferase
24 Histoblood Groups A and B Transferases, Their Gene Structures, and Common O Group Gene Structures
25 Histoblood Group A Variants, O Variants, and Their Alleles
26 Forssman Glycolipid Synthase
Part 5Fucosyltransferases
27 a2-Fucosyltransferases (FUT1, FUT2, and Sec1)
28 a3/4-Fucosyltransferase (FUT3, Lewis Enzyme)
29 a3-Fucosyltransferase-IV (FUT4)
30 a3-Fucosyltransferase-V (FUT5)
31 a3-Fucosyltransferase-VI (FUT6)
32 a3-Fucosyltransferase-VII (FUT7)
33 a3-Fucosyltransferase-IX (FUT9)
34 a6-Fucosyltransferase (FUT8)
Part 6Sialyltransferases
35 ST3Gal-I
36 ST3Gal-II (SAT-IV)
37 ST3Gal-III
38 ST3Gal-IV
39 ST3Gal-V (GM3 Synthase, SAT-I)
40 ST6Gal-I
41 ST6GalNAc-I
42 ST6GalNAc-II
43 ST6GalNAc-III(STY)
44 ST6GalNAc-IV
45 ST8Sia-I (GD3 Synthase, SAT-II)
46 ST8Sia-II (STX)
47 ST8Sia-III
48 ST8Sia-IV (PST-1)
49 ST8Sia-V (SAT-V/SAT-III)
50 CMP-NeuAc Hydroxylase
Part 7Glucuronyltransferases
51 HNK-1 Glucuronyltransferase
52 GAG Glucuronyltransferase-I
53 UDP-Glucose Dehydrogenase
Part 8GAG Synthesis
54 a4-N-Acetylhexosaminyltransferase (EXTL2)
55 Hyaluronan Synthase-1, -2, and -3
56 Heparan Sulfate GlcA/GlcNAc Transferase
57 D-Glucuronyl C5-Epimerase in Heparin/Heparan Sulfate Biosynthesis
Part 9Sulfotransferases
58 Chondroitin 6-Sulfotransferase
59 Keratan Sulfate Gal-6-Sulfotransferase
60 Corneal N-Acetylglucosamine 6-O-Sulfotransferase
61 N-Acetylglucosamine-6-O-Sulfotransferase
62 Intestinal N-Acetylglucosamine 6-O-Sulfotransferase
63 High Endothelial Cell N-Acetylglucosamine
6-O-Sulfotransferase
64 Chondroitin 4-Sulfotransferase
65 HNK-1 Sulfotransferase
66 Galactosaminoglycan Uronyl 2-Sulfotransferase
67 Heparan Sulfate 2-Sulfotransferase
68 Heparan Sulfate 6-Sulfotransferase
69 Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase-1, -2, and -3
70 Heparan Sulfate N-Sulfotransferase-1
71 Heparan Sulfate N-Sulfotransferase-2
72 Heparan Sulfate N-Sulfotransferase-3 and -4
73 bGal 3-O-Sulfotransferase-1, -2, -3, and -4
Part 10 Nucleotide Sugar Transporters
74 UDP-Gal Transporter-1 and -2
75 UDP-GlcNAc Transporter
76 CMP-Sialic Acid Transporter
Part 11 Dolichol Pathway/GPI-Anchor
77 GPI-GlcNAc Transferase: Complex of PIG-A, PIG-C, PIG-H, hGPI1, and PIG-P
78 Dolichol Phospho-Mannose Synthase (DPM1 and DPM2)
79 PIG-B, GPI-Man Transferase III, Man-(Ethanolaminephosphate)Man-GlcN-(Acyl)PI Mannosyltransferase
80 Dolichol Phosphate GlcNAc-1-P Transferase
81 ALG3 Mannosyltransferase
82 ALG6 Glucosyltransferase
Part 12 N-Glycan Processing Enzymes
83 Oligosaccharyltransferase Complex, Ribopho