Mesenchymal Stem Cell Derived Exosomes

The Potential for Translational Nanomedicine
Erscheinungsjahr 2015
ISBN: 978-0-12-800164-6
Verlag: Elsevier Science

Buch, Englisch, 288 Seiten, Format (B × H): 155 mm x 231 mm, Gewicht: 590 g

Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas - cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool.

Autoren/Hrsg.

Tang, Yaoliang

Dawn, Buddhadeb

Fachgebiete

• Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Kardiologie, Angiologie, Phlebologie

Inhaltsverzeichnis

1: Insights into the Mechanism of Exosome Formation and Secretion

2: An Overview of the Proteomic and miRNA Cargo in MSC Derived Exosomes

3: Exosome Function in miRNA-Mediated Paracrine Effects

4: Current Methods in Purification of MSC-Derived Exosomes

5: Stem Cell Extracellular Vesicles: A Novel Cell-Based Therapy for Cardiovascular Diseases

6: The Cardioprotection of Mesenchymal Stem Cell and Anti-Apoptotic microRNA Transfer Through Exosomes

7: Engineered/Hypoxia-Preconditioned MSCs Derived Exosome: Potential Therapeutic Applications

8: Exosome-Based Translational Nanomedicine: The Therapeutic Potential for Drug Delivery

9: Effect of Exosomes from Mesenchymal Stem Cells on Angiogenesis

10: Exosomes for Bone Diseases

11: Diagnostic and Prognostic Applications of MicroRNA-Abundant Circulating Exosomes