Buch, Englisch, 376 Seiten, Format (B × H): 154 mm x 244 mm, Gewicht: 671 g
Buch, Englisch, 376 Seiten, Format (B × H): 154 mm x 244 mm, Gewicht: 671 g
Reihe: Enzyme Inhibitors in Medicine
ISBN: 978-0-415-30673-7
Verlag: CRC Press
Carbonic Anhydrase: Its Inhibitors and Activators provides a state-of-the-art overview of the latest developments and challenges in carbonic anhydrase research. Authors describe the mechanisms of action of specific inhibitors in relation to physiological function, and present previously unpublished research on CA activators. Written by a team of internationally recognized experts, this authoritative edition is a leading reference for bioscientists across many disciplines, as well as novices interested in the latest developments in this complex field. An understanding of the mechanisms through which carbonic anhydrases interact with their inhibitors and activators in complex biological environments is essential in developing novel therapeutic agents for the treatment of disease.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Carbonic anhydrases: catalytic and inhibition mechanisms, distribution, and physiological roles; Acatalytic CAs: carbonic anhydrase related proteins (CARPs); Multiple binding modes observed in X-ray structures of carbonic anhydrase inhibitor complexes and other systems: consequences for structure-based drug design; Development of sulfonamide carbonic anhydrase inhibitors (CAIs); QSAR studies of sulfonamide carbonic anhydrase inhibitors; Metal complexes of heterocyclic sulfonamides as
Carbonic Anhydrase: Its Inhibitors and Activators provides a state-of-the-art overview of the latest developments and challenges in carbonic anhydrase research. Authors describe the mechanisms of action of specific inhibitors in relation to physiological function, and present previously unpublished research on CA activators. Written by a team of internationally recognized experts, this authoritative edition is a leading reference for bioscientists across many disciplines, as well as novices interested in the latest developments in this complex field. An understanding of the mechanisms through which carbonic anhydrases interact with their inhibitors and activators in complex biological environments is essential in developing novel therapeutic agents for the treatment of disease.
This book provides a state-of-the-art overview of the developments in CA and CA-inhibitor research and will be of great interest to medicinal chemists, pharmacologists and professionals involved in novel drug design.
