Zebrafish Protocols for Neurobehavioral Research

2012
ISBN: 978-1-61779-596-1
Verlag: Humana Press

Buch, Englisch, Band 66, 357 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 903 g

Reihe: Neuromethods

Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research.  Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders.  Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Stewart, Adam Michael

Kalueff, Allan V.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Naturwissenschaften Biowissenschaften Biowissenschaften Neurobiologie, Verhaltensbiologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

Part I: Larval Zebrafish Models
 
1. Measuring Larval Zebrafish Behavior: Locomotion, Thigmotaxis, and Startle
            William H.J. Norton
 
2. The Light-Dark Preference Test for Larval Zebrafish
            Peter J. Steenbergen, Michael K. Richardson, and Danielle L. Champagne
 
3. Assessment of Thigmotaxis in Larval Zebrafish
            Stephanie J. Schnörr, Peter J. Steenbergen, Michael K. Richardson, and Danielle L. Champagne
 
4. Zebrafish and Drug Development: A Behavioral Assay System for Probing Nicotine Function in Larval Zebrafish
            Henning Schneider, Eric W. Klee, Karl J. Clark, Andrew M. Petzold, Vanessa L. Mock, Julia M. Abarr, Jennifer L. Behrens, Ryan E. Edelen, Bryan A. Edwards, Joshua S. Hobgood, Meghann E. Pogue, Nishant K. Singh, and Stephen C. Ekker
 
5. Olfactory Evoked Activity Assay for Larval Zebrafish            Ganive Bhinder and Keith B. Tierney
 
6. Qualitative and Quantitative Measurements of the Optokinetic Response in Larval Zebrafish
            Kaspar P. Mueller and Stephan C.F. Neuhauss
 
7. Automated Imaging of Visual Recognition Memory in Larval Zebrafish
            Ruth M. Colwill and Robbert Creton
 
8. Automated Conditioning in Larval Zebrafish
            Ruey-Kuang Cheng and Suresh Jesuthasan
 
9. A Method to Quantify Basal and Stress-Induced Cortisol Response in Larval Zebrafish
            Peter J. Steenbergen, Juriaan R. Metz, Gert Flik, Michael K. Richardson, and Danielle L. Champagne
 
Part II: Adult Zebrafish Models 
10. A Method for Sorting Zebrafish on the Exploratory-Bold Behavioral Axis
            Cory D. Sailer, Sonny J. Radenic, and Brian D. Wisenden
 
11. Nocifensive Behavior in Adult and Larval Zebrafish
            Monica Gomes Lima, Caio Maximino, and Anderson Manoel Herculano
 
12. Use of a Split Depth and Visual Cliff Apparatus to Measure the Diving Response in Zebrafish
            Rachel Blaser and Kelly Goldsteinholm
 
13. Adapting the Open Field Test to Assess Anxiety-Related Behavior in Zebrafish
            John Godwin, Susanna Sawyer, Florence Perrin, Sarah E. Oxendine, and Zachary D. Kezios
 
14. Behavioral and Pharmacological Aspects of Anxiety in the Light/Dark Preference Test
            Juliana Araujo, Caio Maximino, Thiago Marques de Brito, Annanda Waneza Batista da Silva, Silvio Morato, Anderson Manoel Herculano, and Amauri Gouveia, Jr.
 
15. A High Throughput and Inexpensive Assay for Anxiety-Related Behaviors in the Zebrafish, Based on Place Preference and Latency to Feed
            Barrie D. Robison, Maia J. Benner, Matthew L. Singer, and Mary E. Oswald
 
16. Automated Tracking of Zebrafish Shoals and the Analysis of Shoaling Behavior
            Noam Miller and Robert Gerlai
 
17. Assessing Social Behavior Phenotypes in Adult Zebrafish: Shoaling, Social Preference, and Mirror Biting Tests
            Mimi Pham, Jolia Raymond, Jonathan Hester, Evan Kyzar, Siddharth Gaikwad, Indya Bruce, Caroline Fryar, Simon Chanin, Joseph Enriquez, Sidarth Bagawandoss, Ivan Zapolsky, Jeremy Green, Adam Michael Stewart, Barrie D. Robison, and Allan V. Kalueff
 
18. Measuring Effects of Psychostimulants on Egocentric Spatial Learning and Memory in Adult Zebrafish
            Rabia Nasir, Tenzin Choezom, Jennifer Cunningham, Benjamin Bajaj, Cristina Rubi, Jonathan Butler, Kathryn Arroyo, and Joseph A. Schroeder
 
19. Cued Fear Conditioning in Zebrafish (Danio rerio)
            Masakazu Agetsuma, Tazu Aoki, Ryo Aoki, and Hitoshi Okamoto
 
20. Assessing Learning and Memory Through the Active Avoidance Paradigm
            Xiaojuan Xu and Stefan Goetz
 
21. Assessing Habituation Phenotypes in Adult Zebrafish: Intra- and Inter-Trial Habituation in the Novel Tank Test
            Jolia Raymond, Simon Chanin, Adam Michael Stewart, Evan Kyzar, Siddharth Gaikwad, Andrew Roth, Indya Bruce, Caroline Fryar, Danielle Varga, Joseph Enriquez, Sidarth Bagawandoss, Mimi Pham, Ivan Zapolsky, Jeremy Green, D