Phosphoinositides in Subcellular Targeting and Enzyme Activation

2004
ISBN: 978-3-540-00950-4
Verlag: Springer Berlin Heidelberg

Buch, Englisch, Band 282, 209 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 554 g

Reihe: Current Topics in Microbiology and Immunology

Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.

Zielgruppe

Research

Autoren/Hrsg.

Stenmark, Harald

Fachgebiete

• Naturwissenschaften Biowissenschaften Lipidologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

List of Contents.- Phosphoinositide Involvement in Phagocytosis and Phagosome Maturation.- Regulation of Endocytosis by Phosphatidylinositol 4,5-Biphosphate and ENTH Proteins.- Membrane Targeting by Pleckstrin Homology Domains.- Protein Targeting to Endosomes and Phagosomes via FYVE and PX Domains.- Regulation of the Actin Cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in Neutrophil Function.- Nuclear Phosphoinositides and Their Functions.