Stack / Fishman Ovarian Cancer

Erscheinungsjahr 2013
ISBN: 978-1-4757-3587-1
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 107, 387 Seiten, eBook

Reihe: Cancer Treatment and Research

Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumor-specific therapeutics. Ovarian carcinogenesis, invasion, and metastatic dissemination require a complex cascade of interrelated genetic, molecular, and biochemical events that regulate the neoplastic transition of normal ovarian surface epithelium. This volume summarizes recent advances in ovarian cancer detection and treatment and provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A more detailed understanding of these processes may ultimately translate into the development of novel approaches for the detection and control of ovarian cancer.

Zielgruppe

Research

Autoren/Hrsg.

Stack, M. Sharon

Fishman, David A.

Inhaltsverzeichnis

1. The Scientific Basis of Early Detection of Epithelial Ovarian Cancer.- 2. Risk Assessment and Genetic Testing.- 3. Early Detection of Ovarian Cancer: Promise and Reality.- 4. Current Diagnosis and Treatment Modalities for Ovarian Cancer.- 5. Ultrasound and Ovarian Cancer.- 6. Gene Therapy.- 7. Normal Ovarian Surface Epithelium.- 8. Cytopathology of the Ovary.- 9. Telomerase and Malignant Transformation.- 10. Homeobox Gene Expression in Ovarian Cancer.- 11. EGF/ErbB Receptor Family in Ovarian Cancer.- 12. Critical Role of Lysophospholipids in the Pathophysiology, Diagnosis, Management of Ovarian Cancer.- 13. Expression of CSF-1 and Its Receptor CSF-1R in Non-Hematopoietic Neoplasms.- 14. Role of Inhibins and Activins in Ovarian Cancer.- 15. Adhesion Molecules.- 16. Ovarian Cancer-Associated Proteinases.- 17. Angiogenesis and Metastasis.