Buch, Englisch, 376 Seiten, Format (B × H): 178 mm x 254 mm, Gewicht: 453 g
Reihe: Frontiers in Neuroscience
Wiring the Brain
Buch, Englisch, 376 Seiten, Format (B × H): 178 mm x 254 mm, Gewicht: 453 g
Reihe: Frontiers in Neuroscience
ISBN: 978-1-032-75616-5
Verlag: Taylor & Francis Ltd
This is a second edition of a book that provides an overview of the most current findings on the diverse roles played by astrocyte in CNS function and dysfunction with emphasis on its cellular connections.
Astrocytes are highly elaborated cells and likely the only neural cells that simultaneously establish associations with different cellular types. The fine processes of astrocytes are found nearby practically all cellular types in the central nervous system (CNS), including astrocytes themselves, neurons, oligodendrocytes, and brain endothelial cells. Such close morphological associations, together with the fact that astrocytes express a multitude of ion channels, transporters and membrane receptors, endows these cells with the unique capability to sense and influence diverse CNS functions.
Disruption of these elaborated connections and altered astrocyte polarization are implicated in numerous pathological conditions such as epilepsy, stroke, leukodystrophies, Alzheimer and Autism, and also certain psychiatric disorders, major depression and schizophrenia.
Zielgruppe
Academic, Postgraduate, and Professional Reference
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Biowissenschaften Zellbiologie
- Naturwissenschaften Biowissenschaften Biowissenschaften
- Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
Weitere Infos & Material
1. What is an astrocyte: Diversity of structures and functions. 2. Gap junctions and Aquaporins. 3. Adhesion molecules in astrocytes. 4. Multi scale astrocyte-neuron communication. 5. Blood-Brain-Barrier and the Neural-Vascular Unit. 6. Oligodendrocytes: Gateway to the panglial syncytium. 7. Critical role of astrocytes in the development of epilepsy. 8. The Role of Glial Pathology in Autism Spectrum Disorders. 9. Astrocytes in Aging and Alzheimer’s Disease. 10. Astrocytes in Stroke. 11. Astrocytes in Depression: insights from postmortem human studies and animal models.