Sigel The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3

1. Auflage 2007
ISBN: 978-0-470-02814-8
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 678 Seiten, E-Book

Reihe: Metal Ions in Life Sciences

Helmut Sigel, Astrid Sigel and Roland K.O. Sigel, in closecooperation with John Wiley & Sons launch a new Series"Metal Ions in Life Sciences".
There exists a whole range of books on Cytochromes P450, butnone with the focus of this volume. This new volume in the Seriesconcentrates on current hot topics in the area and tries to workout the underlying common developments.
As a result the reader will find a systematic account of newresults in this exciting research area. The table of contentsgives an idea on the wide span of chapters, starting with overviewsand the presentation of specific systems, and ending withchapters on carbon-carbon bond cleavage by P450 sytems, drugmetabolism as catalyzed by P450 systems, decomposition ofxenobiotics by P450 enzymes and design and engineering of new P450systems.

Autoren/Hrsg.

Sigel, Astrid

Sigel, Helmut

Sigel, Roland K. O.

Über Autor(innen)

Astrid Sigel has studied languages and was an editor of theMetal Ions in Biological Systems series (until Volume 44) and alsoof the Handbooks on Toxicity of Inorganic Compounds (1988), onMetals in Clinical and Analytical Chemistry (1994; both with H.G.Seiler), and on Metalloproteins (2001; with Ivano Bertini) (Dekker,New York).
Helmut Sigel is Emeritus Professor (2003) of InorganicChemistry at the University of Basel, Switzerland, and a previouseditor of the MIBS series until Volume 44. He serves on variouseditorial and advisory boards, published over 300 articles on metalion complexes of nucleotides, coenzymes, and other ligands ofbiological relevance, and lectured worldwide. He was namedProtagonist in Chemistry (2002) by ICA (issue 339); among furtherhonors are the P. Ray Award (Indian Chemical Society, of which heis also an Honorary Fellow), the Werner Award (Swiss ChemicalSociety), a Doctor of Science honoris causa degree (KalyaniUniversity, India), appointments as Visiting Professor (e.g.,Austria, China, UK) and Endowed Lectureships.
Roland K.O. Sigel is Assistant Professor (2003) ofInorganic Chemistry at the University of Zürich, Switzerland,endowed with a Förderungsprofessur of the Swiss NationalScience Foundation. He received his doctoral degree summa cum laude(1999) from the University of Dortmund, Germany, working withBernhard Lippert; thereafter he spent nearly three years atColumbia University, New York, USA, in the group of Anna Marie Pyle(now Yale University); during the six years abroad he receivedseveral fellowships from various sources. His research focuses onthe structural and catalytic role of metal ions in ribozymes,especially group II introns, and on related topics. He was also aneditor of Volumes 43 and 44 of the MIBS series.