E-Book, Englisch, 336 Seiten, E-Book
Shulman / Rothman Brain Energetics and Neuronal Activity
1. Auflage 2005
ISBN: 978-0-470-02051-7
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
Applications to fMRI and Medicine
E-Book, Englisch, 336 Seiten, E-Book
ISBN: 978-0-470-02051-7
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)
This book is unique in linking in vivo ¯13C NMRmeasurements of neuronal activity and energetics with applicationsto functional imaging and certain disease states It provides afundamental neurochemical explanation of brain activity applicableto functional imaging, theories of neuronal activity and diseasestates, e.g. epilepsy, psychiatric diseases and developmentaldisorders.
* Novel and potentially controversial
* Will inspire future research directions
Autoren/Hrsg.
Weitere Infos & Material
Contributors.
Foreword.
Section A: Background.
1. Introduction (Douglas L. Rothman and Robert G. Shulman).
2. Energy Metabolism in Neural Tissues in vivo at Rest and inFunctionally Altered States (Louis Sokoloff).
3. Techniques-MRS, fMRI, 13C NMR, Indirect Detection of13C (Robin de Graaf).
4. Metabolic Modeling Analysis of Brain Metabolism (GraemeMason).
Section B: Neuroenergetics and Activity.
5. Cerebral Energetics and Neurotransmitter Fluxes (Nicola R.Sibson).
6. NMR Studies of the Metabolism and Energetics of GABANeurotransmitter Pathways (Kevin L. Behar and Douglas L.Rothman).
7. Neural Energy Consumption and the Representation of MentalEvents (Simon B. Laughlin and David Attwell).
8. Imaging Cerebral Metabolic Rate of Oxygen Consumption (CMRO2)using 17O NMR Approach at Ultrahigh Field (Wei Chen, Xiao-Hong Zhuand Kamil Ugurbil).
9. Deriving Changes in CMRO2 from Calibrated fMRI (FahmeedHyder).
10. Relationship between CMRO2 and Neuronal Activity (FahmeedHyder and Hal Blumenfeld).
Section C: Clinical Beginnings.
11. NMR Studies of Bioenergetic Impairment in Human Epilepsy(Hoby P. Hetherington, Jullie W. Pan and Dennis D. Spencer).
12. MRS Studies of the Role of Altered Glutamate and GABANeurotransmitter Metabolism in the Pathophysiology of Epilepsy(Ognen A. C. Petroff and Dennis D. Spencer).
13. The Role of Altered Energetics of Neurotransmitter Systemsin Psychiatric Disease (Graeme F. Mason).
Section D: Brain and Mind.
14. Long-term Memory: Do Incremental Signals Reflect Engagementof Cognitive Processes? (Jed A. Meltzer and R. Todd Constable).
15. Using fMRI to Study the Mind and Brain (Bruce E.Wexler).
16. Brain and Mind: an NMR Perspective (Robert G. Shulman andFahmeed Hyder).
17. The Role of the NMR Baseline Signal in the Study ofConsciousness: the Restless Brain (Robert G. Shulman).
Index.
