Shi / Alfano | Deep Imaging in Tissue and Biomedical Materials | E-Book | sack.de
E-Book

E-Book, Englisch, 542 Seiten

Shi / Alfano Deep Imaging in Tissue and Biomedical Materials

Using Linear and Nonlinear Optical Methods
Erscheinungsjahr 2017
ISBN: 978-1-351-79739-9
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

Using Linear and Nonlinear Optical Methods

E-Book, Englisch, 542 Seiten

ISBN: 978-1-351-79739-9
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)



The use of light for probing and imaging biomedical media is promising for the development of safe, noninvasive, and inexpensive clinical imaging modalities with diagnostic ability. The advent of ultrafast lasers has enabled applications of nonlinear optical processes, which allow deeper imaging in biological tissues with higher spatial resolution. This book provides an overview of emerging novel optical imaging techniques, Gaussian beam optics, light scattering, nonlinear optics, and nonlinear optical tomography of tissues and cells. It consists of pioneering works that employ different linear and nonlinear optical imaging techniques for deep tissue imaging, including the new applications of single- and multiphoton excitation fluorescence, Raman scattering, resonance Raman spectroscopy, second harmonic generation, stimulated Raman scattering gain and loss, coherent anti-Stokes Raman spectroscopy, and near-infrared and mid-infrared supercontinuum spectroscopy. The book is a comprehensive reference of emerging deep tissue imaging techniques for researchers and students working in various disciplines.

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Weitere Infos & Material


Overview of Second- and Third-Order Nonlinear Optical Processes for Deep Imaging
Sangeeta Murugkar and Robert W. Boyd

Complex Light Beams
Enrique J. Galvez

Gaussian Beam Optical Parameters in Multi-Photon Excitation Fluorescence Imaging
Lingyan Shi, Adrián Rodríguez-Contreras, and Robert R. Alfano

The Optics of Deep Optical Imaging in Tissues Using Long Wavelengths
Steven L. Jacques

Light Propagation and Interaction in Highly Scattering Media for Deep Tissue Imaging
W. B. Wang, Lingyan Shi, Luyao Lu, Laura A. Sordillo, L. Wang, S. K. Gayen, and R. R. Alfano

Application of Nonlinear Microscopy in Life Sciences
Zdenek Svindrych and Ammasi Periasamy

Smart Biomarker-Coated PbS Quantum Dots for Deeper Near-Infrared Fluorescence Imaging in the Second Optical Window
Takashi Jin, Akira Sasaki, and Yukio Imamura

Biomedical Applications in Probing Deep Tissue Using Mid-Infrared Supercontinuum Optical Biopsy
Angela B. Seddon

Light Propagation in Turbid Tissue-Like Scattering Media
Alexander Bykov, Alexander Doronin, and Igor Meglinski

Overview of the Cumulant Solution to Light Propagation Inside a Turbid Medium and Its Applications in Deep Imaging Beyond the Diffusion Approximation
Min Xu, Cai Wei, and Robert R. Alfano

Deep Imaging of Prostate Cancer Using Diffusion Reconstruction of Banana Paths with Near Infrared Prostatoscope Analyzer
Yang Pu, Wubao Wang, Min Xu, James A. Eastham, and Robert R. Alfano

Terahertz Propagation in Tissues and Its Thickness Limitation
Burcu Karagoz and Hakan Altan

Detection of Brain Tumors Using Stimulated Raman Scattering Microscopy
Spencer Lewis and Daniel Orringer

Chemical and Molecular Imaging of Deep Tissue through Photoacoustic Detection of Chemical Bond Vibrations
Yingchun Cao and Ji-Xin Cheng

Deep Tissue Imaging: Acoustic and Thermal Wave Propagation and Light Interactions in Tissue
Idan Steinberg, Asaf Shoval, Michal Balberg, Adi Sheinfeld, Michal Tepper, and Israel Gannot

Using the Transmission Matrix to Image Disordered Media
Matthieu Davy, Sylvain Gigan, and Azriel Z. Genack


Lingyan Shi is a research scientist at Columbia University, USA. Her current research focuses on metabolic imaging with stimulated Raman scattering microscopy. She was a research associate studying deep imaging and drug delivery in the brain at the Institute for Ultrafast Spectroscopy and Lasers, the City College of New York, USA, where she received her PhD in biomedical engineering.

Robert R. Alfano is a distinguished professor of science and engineering at the City College of New York. He has pioneered many applications of light and photonics technology to study biological, biomedical, and condensed matter systems using optical spectroscopy and imaging. He discovered and has used supercontinuum. Prof. Alfano is a fellow of the American Physical Society, the Optical Society, and the Institute of Electrical and Electronics Engineers.



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