Shapiro / Risbud The Intervertebral Disc

Molecular and Structural Studies of the Disc in Health and Disease
1. Auflage 2013
ISBN: 978-3-7091-1535-0
Verlag: Springer Vienna
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 446 Seiten

The intervertebral disc is a complex structure that separates opposing vertebrae, permits a wide range of motion, and accommodates high biomechanical forces. Disc degeneration leads to a loss of function and is often associated with excruciating pain.Written by leading scientists and clinicians,  the first part of the book provides a review of the basic biology of the disc in health and disease. The second part considers strategies to mitigate the effects of disc degeneration and discusses the possibility of engineering replacement tissues. The final section is devoted to approaches to model normal development and elucidate the pathogenesis of degenerative disc disease using animal, organ and cell culture techniques.  The book bridges the gap between the basic and clinical sciences; the target audience includes basic scientists, orthopaedists and neurologists, while at the same time appealing to the needs of  graduate students, medical students, interns and fellows.

Irving M. Shapiro BDS, PhDMakarand Risbud, Ph.D.Division of Orthopaedic Research, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA

Autoren/Hrsg.

Shapiro, Irving M.

Risbud, Makarand V.