Metabolism at a Glance

4. Auflage 2017
ISBN: 978-0-470-67471-0
Verlag: John Wiley and Sons Ltd

Buch, Englisch, 144 Seiten, Format (B × H): 283 mm x 332 mm, Gewicht: 761 g

Metabolism at a Glance presents a concise, illustrated summary of metabolism in health and disease. This essential text is progressively appropriate for introductory through to advanced medical and biochemistry courses. It also provides a succinct review of inborn errors of metabolism, and reference for postgraduate medical practitioners and biomedical scientists who need a resource to quickly refresh their knowledge.

Fully updated and extensively illustrated, this new edition of Metabolism at a Glance is now in full colour throughout, and includes new coverage of sports biochemistry; the metabolism of lipids, carbohydrates and cholesterol; glyceroneogenesis, alpha-oxidation and omega-oxidation of fatty acids. It also features the overlooked "Krebs Uric Acid Cycle".
Metabolism at a Glance offers an accessible introduction to metabolism, and is ideal as a revision aid for students preparing for undergraduate and USMLE Step 1 exams.

Autoren/Hrsg.

Salway, J. G.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Ernährungsmedizin, Diätetik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Stoffwechselstörungen

Inhaltsverzeichnis

Preface ix

Acknowledgements x

Part 1 Energy metabolism

1 Introduction to metabolic pathways 2

2 Biosynthesis of ATP I: ATP, the molecule that powers metabolism 4

3 Biosynthesis of ATP II: mitochondrial respiratory chain 6

4 Oxidation of cytosolic NADH: the malate/aspartate shuttle and glycerol phosphate shuttle 8

5 Metabolism of glucose to provide energy 10

6 Metabolism of one molecule of glucose yields 31 (or should it be 38?) molecules of ATP 12

7 Anaerobic metabolism of glucose and glycogen to yield energy as ATP 14

8 2,3-Bisphosphoglycerate (2,3-BPG) and the red blood cell 16

9 Metabolism of triacylglycerol to provide energy as ATP 18

Part 2 Carbohydrate metabolism

10 Metabolism of glucose to glycogen 20

11 Glycogen metabolism I 22

12 Glycogen metabolism II 24

13 Glycogen metabolism III: regulation of glycogen breakdown (glycogenolysis) 26

14 Glycogen metabolism IV: regulation of glycogen synthesis (glycogenesis) 28

15 Pentose phosphate pathway: the production of NADPH and reduced glutathione 30

16 Regulation of glycolysis: overview exemplified by glycolysis in cardiac muscle 32

17 Glycolysis in skeletal muscle: biochemistry of sport and exercise 34

18 Regulation of gluconeogenesis 36

19 Regulation of Krebs cycle 38

20 Mammals cannot synthesize glucose from fatty acids 40

21 Supermouse: overexpression of cytosolic PEPCK in skeletal muscle causes super-athletic performance 42

22 Sorbitol, galactitol, glucuronate and xylitol 44

23 Fructose metabolism 46

24 Ethanol metabolism 48

Part 3 Fat metabolism

25 Pyruvate/malate cycle and the production of NADPH 50

26 Metabolism of glucose to fat (triacylglycerol) 52

27 Metabolism of glucose to fatty acids and triacylglycerol 54

28 Glycolysis and the pentose phosphate pathway collaborate in liver to make fat 56

29 Esteri

Über Autor(innen)

Jack Salway was Senior Lecturer within the Faculty of Health and Medical Sciences at the University of Surrey until 2008.