Functional Connectivity of the Human Brain

From Mechanisms to Clinical Applications
Erscheinungsjahr 2025
ISBN: 978-0-443-19099-5
Verlag: Elsevier Science

Buch, Englisch, 450 Seiten, Format (B × H): 152 mm x 229 mm

Functional Connectivity of the Human Brain: From Mechanisms to Clinical Applications is a comprehensive review of mechanisms and analysis of methods of functional connectivity to map brain organization in healthy individuals and sick patients. Providing full coverage of the discipline for a wide audience of different research and clinical specialists, this volume begins with descriptions of mechanisms of functional connectivity and methodological approaches to quantify it, followed by a focus on how functional connectivity has been used to describe brain function in healthy people and to characterize network disruption in diseased conditions.

This practical balance in book structure is suitable for readers with a technical or clinical orientation, providing background that is easy to approach for clinicians or scientists. Chapters examine fMRI and electrophysiological techniques, brain maturation, aging, and cognitive neurosciences, as well as functional connectivity in neuroinflammatory, neurodegenerative, and neuropsychiatric conditions. Future perspectives look forward to functional connectivity in multimodal analysis, artificial intelligence, and more. This book will be of use to a wide audience working on functional connectivity experiments, as well as any courses on the topic.

Autoren/Hrsg.

Rocca, Maria Assunta

Filippi, Massimo

Fachgebiete

• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Radiologie, Bildgebende Verfahren
• Interdisziplinäres Wissenschaften Wissenschaften: Forschung und Information Forschungsmethodik, Wissenschaftliche Ausstattung

Inhaltsverzeichnis

1. Functional connectivity: definition and signal origins
2. Assessing functional connectivity: the role of functional MRI and electrophysiological techniques
3. Analysis methods for functional connectivity: from seed-regions to data-driven approaches
4. Causal connections in the brain: from functional to causal connectivity
5. Exploring functional connectivity using graph theoretical analysis
6. Time-varying analysis of functional connectivity
7. Trajectories of brain functional connectivity in brain maturation
8. Trajectories of brain functional connectivity in brain aging
9. Application of functional connectivity to cognitive neurosciences
10. Functional connectivity in neuroinflammatory conditions
11. Functional connectivity in neurodegenerative conditions
12. Functional connectivity in neuropsychiatric diseases
13. Current limitations in functional connectivity assessment: suggestions for analysis improvements
14. Future perspectives of functional connectivity: multimodal analysis, artificial intelligence, and more

Über Autor(innen)

Filippi, Massimo
Massimo Filippi, MD, is Full Professor of Neurology at Vita-Salute San Raffaele University, Director of the Residency School in Neurology, President of the Bacherlor's Degree in Physiotherapy, Chair of the Neurology and Neurorehabilitation Units, Director of the MS Center, Director of the Neurophysiology Service, and Director of the Neuroimaging Research Unit at IRCCS Scientific Institute San Raffaele, Milan. His research activity has always focused on the definition of the mechanisms underlying various neurological conditions, including multiple sclerosis, neurodegenerative disorders, and migraine. As Director of the of the Neuroimaging Research Unit, he coordinated the MRI acquisition and analysis of several large-scale international MRI-monitored trials of multiple sclerosis. He is member of various national and international Scientific Societies and Boards and for some of them, he holds or has held institutional roles. He is Editor-in-Chief of the Journal of Neurology, Associate Editor of Human Brain Mapping, Radiology, and Neurological Sciences.