Robinson The Biochemistry of Alkaloids

Erscheinungsjahr 2013
ISBN: 978-3-662-01015-0
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 3, 152 Seiten, eBook

Reihe: Molecular Biology, Biochemistry and Biophysics Molekularbiologie, Biochemie und Biophysik

The alkaloids were of great importance to mankind for centuries, long before they were recognized as a chemical class. The influence they have had on literature is hinted at by some of the quotations I have used as chapter headings. Their in fluence on folklore and on medicine has been even greater. The scientific study of alkaloids may be said to have begun with the isolation of morphine by SERTURNER in 1804. Since that time they have remained of great interest to chemists, and now in any month there appear dozens of publications dealing with the isolation of new alkaloids or the determination of the structures of previously known ones. The area of alkaloid biochemistry, in comparison, has received little attention, and today is much less developed. There is a certain amount of personal arbitrariness in defining "biochemistry", as there is in defining "alkaloid", and this arbitrariness is doubtless compounded by the combination. Nevertheless, it seems to me that in any consideration of the bio chemistry of a group of compounds three aspects are always worthy of attention pathways of biosynthesis, function or activity, and pathways of degradation. For the alkaloids, treatment of these three aspects is necessarily lopsided. Much has been learned about routes of biosynthesis, but information on the other aspects is very scanty. It would be possible to enter into some speculation regarding the biosyn thesis of all the more than 1,000 known alkaloids.

Zielgruppe

Research

Autoren/Hrsg.

Robinson, Trevor

Inhaltsverzeichnis

1 Introduction.- 2 General Theories of Alkaloid Biosynthesis.- Bibliography..- 3 Simple Amino Acid Derivatives and Protoalkaloids.- 4 Pyrrolidine, Piperidine, and Pyridine Alkaloids.- Piperidine Alkaloids.- Pyridine Alkaloids.- Trigonelline.- Ricinine.- Tobacco Alkaloids.- Nicotinic Acid.- 5 Tropane Alkaloids.- 6 Lupine Alkaloids.- 7 Isoquinoline Alkaloids.- 8 Aporphine and Morphinan Alkaloids.- 9 Amaryllidaceae Alkaloids and Colchicine.- 10 Indole Alkaloids.- Ergot Alkaloids.- 11 Quinolines and Other Alkaloids Related to Anthranilic Acid 92 Bibliography.- 12 Some Miscellaneous Alkaloids.- Pyrrolizidine Alkaloids..- Purine Alkaloids.- Benzoxazoles.- Lycopodium Alkaloids.- Betacyanins and Betaxanthins.- Imidazole Alkaloids.- 13 Terpenoid and Steroid Alkaloids.- Diterpenoids.- Steroids.- 14 Metabolism of Alkaloids by Bacteria and Animals.- Animals.- Microorganisms.- Higher plants.- Bibliography..- 15 Biochemical Pharmacology of Alkaloids.- Addendum.