Cancer Immunology and Genetics: An Interdisciplinary Approach

Erscheinungsjahr 2025
ISBN: 978-3-031-99373-2
Verlag: Springer

Buch, Englisch, 841 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 1435 g

Reihe: Interdisciplinary Cancer Research

The “Cancer Immunology and Genetics: An Interdisciplinary Approach” is the twenty third volume of the “Interdisciplinary Cancer Research” series, publishes comprehensive volume on cancer immunology and genetics. The volume starts with a chapter on thymic stromal lymphopoietin and cancers, followed by other chapters on immunogenic cancer cell death and epigenetics. Tumor microenvironments, innate lymphoid cells, and tumor-associated macrophages are explained in subsequent chapters. Other chapters focus on telomere maintenance in cancer cells, single nucleotide polymorphisms, Human leukocyte antigen, long non-coding RNA, and microRNA as oncogenic features as well as diagnostic and therapeutic approaches. Finally, genome editing, targeting epigenetic readers, and pharmacogenomics of cancer chemotherapy are discussed in the last chapters. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for those who wish to have an update on cancer immunology and genetics.

Zielgruppe

Research

Autoren/Hrsg.

Rezaei, Nima

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

Thymic Stromal Lymphopoietin and Malignancies.- Immunogenic Cancer Cell Death.- Epigenetics in Cancer Biology.- Microenvironment of Normal Looking Tissues Adjacent to Cancer: Matters Arising.- The Paradoxical Role of Immune Response in Cancer Microenvironment.- T Cells and Their Roles in Tumor Microenvironments.- Role of Regulatory Immune Cells in Tumour Microenvironment (TME).- Exploring the Metabolic Reprogramming of Immune Cells in Tumor Microenvironments.- Innate Lymphoid Cells in Cancer Immunobiology and Immunotherapy.- Tumor-Associated Macrophages and Their Role in Cancer Progression and Treatment Strategies.- Tumor-associated Macrophages in Colorectal Cancer.- Impact of Siglec-Sialic Acid Axis on the Cancer Immune Response.- Mechanisms on Telomere Maintenance in Cancer Cells.- Classification of SNPs, Tips from the Basic Knowledge to the Clinical Outcomes.- The Potential Role of HLA-G on Cancer.- Two Sides of the Same Coin: Genes Involvement in Neurodegeneration and Cancer.- MicroRNA: Exploring Their Multifaceted Role in Cancer.- Role of miRNAs in cancer: Main Therapeutic, Diagnostic, and Oncogenic Features.- LncRNA: Secret Regulators of Cancer Metabolism.- Structure and Function of The H19 Long Non-Coding RNA in Cancer.- Genome Editing: Current Approaches and the Road Ahead in Cancer Research and Therapeutics.- Targeting Epigenetic Readers Using Small Molecule Binders and PROTAC Degraders.- Pharmacogenomics of Cancer Chemotherapy: Transporter Polymorphisms and Drug Response.- Genetic Variants Associated with Morphine Treatment in Cancer.

Über Autor(innen)

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital.  Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research and Technologies, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the Founder of Universal Scientific Education and Research Network (USERN). Prof. Rezaei has already been the Director of more than two hundred research projects and has designed and participated in several international collaborative projects. Prof. Rezaei is the editor, editorial assistant, or editorial board member of more than fifty international journals. He has edited more than one hundred international books, has presented more than a thousand lectures/posters in congresses/meetings, and has published more than 1,500 scientific papers in the international journals.