Pharmaceutical Biotechnology in Drug Development

Erscheinungsjahr 2023
ISBN: 978-0-443-19135-0
Verlag: Elsevier Science Publishing Co Inc

Buch, Englisch, 236 Seiten, Format (B × H): 229 mm x 152 mm, Gewicht: 396 g

Pharmaceutical Biotechnology in Drug Development summarizes key concepts and the latest developments of biotechnology applied to the development of biopharmaceuticals. Chapters present a comprehensive collection of introductory biotechnology technologies and their modern concepts and cover pharmacokinetic and pharmacodynamic behavior of biopharmaceuticals and modification techniques of amino acids and nucleic acid. Other sections focus on topics such as gene therapy, immunological preparations and nanoparticles which are the major contributions of pharmaceutical biotechnology. Final chapters discuss emerging techniques in the field of pharmaceutical biotechnology to meet current patient and health care demand.

This book is an essential reference useful for pharmaceutical scientists, clinicians and academic researchers who want easy access to up-to-date practices of pharmaceutical biotechnology. Corporate researchers will also benefit from this book's succinct and objective content structure.

Autoren/Hrsg.

Rehman, Kanwal

Irshad, Kanwal

Akash, Muhammad Sajid Hamid

Chen, Shuqing

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

1. Introduction to modern concepts in pharmaceutical biotechnology and drug development
2. Pharmacokinetic and pharmacodynamics of biotechnology products
3. Role of biotechnology in amino acids modification
4. Role of biotechnology in nucleic acid modification
5. Monoclonal antibodies: Development, characterization and therapeutic application
6. Development of nanoparticles: recent developments and future prospects
7. Production of biopharmaceuticals from genetically modified organisms
8. Metabolomics as bioanalytical approach for pharmaceutical biotechnology in drug development
9. New biological targets for drug discovery and development
10. Signaling pathways of membrane-spanning receptors for drug discovery and development

Über Autor(innen)

Irshad, Kanwal
Dr. Kanwal Irshad is working as PhD scholar at Department of Pharmaceutical Chemistry in Government College University Faisalabad, Pakistan. She has done her MPhil from Government College University Faisalabad, Pakistan. She completed her bachelor's (Doctor of Pharmacy) from University of Agriculture, Faisalabad. She has done excellent work on exploring the effect of arsenic on hepatoxicity and nephrotoxicity and their amelioration by bioactive compounds. She has published 5 articles and 8 book chapters with international book publishers. She has received HEC PhD indigenous scholarship for completion of PhD by Higher Education Commission (HEC) of Pakistan. Currently, she is focusing on the investigation of different molecular pathways of arsenic in neurological disorders and their treatment strategies by naturally occurring bioactive compounds.

Rehman, Kanwal
Dr. Kanwal Rehman is working as an Associate Professor at the Department of Pharmacy in The Women University, Multan, Pakistan. Dr. Rehman received her PhD in Pharmacology from Zhejiang University, China. She nurtures
a keen interest in the pathogenesis of metabolic disorders and new therapeutic modalities for its treatment. Currently, she
is focusing on the investigation of the role of pharmacogenomics based upon gene polymorphism on various molecular and
metabolic pathways that are involved in mitogenic disorders and treatment strategies, like natural biogenic compounds against different risk factors of metabolic disorders, including pancreatitis, cardiometabolic disorders, and hormonal imbalance. Dr. Rehman has also been awarded the Research Productivity Award by the Pakistan Council for Science and Technology, Pakistan; the PAS Gold Medal from the Pakistan Academy of Sciences; and the A.R. Shakoori Gold Medal from the Zoological Society of Pakistan.