Advancements in Modeling-Based Therapeutics and Technology for Chronic Diseases

Erscheinungsjahr 2025
ISBN: 978-0-443-33877-9
Verlag: Elsevier Science

Buch, Englisch, 512 Seiten, Format (B × H): 191 mm x 235 mm

Advancements in Modeling-Based Therapeutics and Technology for Chronic Diseases delves into the crucial role of animal and cellular models in comprehending the intricate mechanisms of chronic diseases. The book emphasizes the importance of these models in predicting disease progression, testing new therapeutic approaches, and understanding how environmental and genetic factors interplay in the development of long-term health conditions. With a multidisciplinary approach, it bridges the gap between experimental research and clinical applications, offering insights into not only disease management but also the future of personalized medicine.

The book also sheds light on emerging technologies, including bioinformatics tools and in silico modeling, which further enhance our ability to tackle chronic diseases. It explores how these advancements are transforming research methodologies and providing novel solutions for diagnosis and treatment. Additionally, it highlights collaborative strategies between researchers, clinicians, and technologists, stressing the importance of integrated efforts in addressing global health challenges effectively.

Autoren/Hrsg.

Rai, Sachchida Nand

Singh, Santosh Kumar

Singh, Veer

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften

Inhaltsverzeichnis

Section 1: Chronic Diseases, Modeling, and Therapeutic Strategies
1. Unravelling the complexity of chronic diseases: an introductory exploration
2. Comparative information of different animal models used in chronic diseases
3. Precision medicine: tailoring therapeutics through advanced modeling strategies
4. Personalized drug design: from models to therapeutics
5. Advancements in biomarker discovery and validation for targeted therapies
6. Advancement in the animal model-based therapeutics in neurodegenerative diseases
7. Cellular models of chronic diseases: from bench to bedside
8. Toxin induced animal models in Parkinson’s disease: recent updates
9. Immunotherapy modeling: harnessing the immune system in chronic disease treatment
10. The Role of transnational models for the management of chronic diseases

Section 2: Technological Innovations in Chronic Disease Management
11. Gene editing technologies: transformative approaches in chronic disease treatment
12. Innovations in imaging technologies for disease modeling and monitoring
13. Computational tools and techniques for disease modeling: bridging the gap
14. Integrated systems biology approaches in chronic disease research

Section 3: Ethical and Regulatory Considerations
15. Ethical considerations in transnational chronic disease management models
16. Exploring ethical dilemmas and regulatory obstacles in modeling-based therapeutics: addressing data privacy concerns

Über Autor(innen)

Singh, Santosh Kumar
Santosh Kumar Singh is a Senior Scientist at the Centre of Experimental Medicine & Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Singh, Veer
Dr. Veer Singh is currently working as Young Scientist (Department of Health Research) at the Department of Biochemistry, ICMR-Rajendra Memorial Research Institute of Medical Sciences, Patna, India. He received his PhD from the Indian Institute of Technology (Banaras Hindu University), Varanasi. He has more than 45 publications with Internationally reputed publishers. He published two Indian patents. His area of work involves Environmental contamination and human health. He is also reviewer and guest editor of reputed publishers.

Rai, Sachchida Nand
Dr. Sachchida Nand Rai is a Biochemistry Research Associate at Banaras Hindu University's Institute of Science. He obtained his MSc in Biochemistry from Purvanchal University, India, and his PhD in Biochemistry from Banaras Hindu University, India. Dr. Rai researches the anti-oxidative and anti-neuroinflammatory properties of phytochemicals for the treatment of neurodegenerative diseases. He is a lifetime member of the Indian Academy of Neuroscience.