Process Intensification in the Manufacturing of Biotherapeutics

Erscheinungsjahr 2022
ISBN: 978-0-323-91355-3
Verlag: William Andrew Publishing

Buch, Englisch, 200 Seiten, Format (B × H): 152 mm x 229 mm, Gewicht: 450 g

Process Intensification in the Manufacturing of Biotherapeutics, Volume 59 in the Advances in Chemical Engineering series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as Evolution and design of continuous bioreactors for the production of biologics, Continuous countercurrent chromatography for the downstream processing of bioproducts: A focus on flow-through technologies Application of multicolumn countercurrent solvent gradient purification to the polishing of therapeutic proteins, Continuous precipitation technologies for the recovery of bioproducts, Continuous Recovery and Purification of Bioproducts on the Basis of Adsorption Technology, General Platform for Development of Integrated Continuous Downstream Processes, and more

Zielgruppe

<p>Researchers, students, and academics in the field of chemical engineering</p>

Autoren/Hrsg.

Weitere Mitwirkende

Moscatelli, Davide

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Chemische Verfahrenstechnik
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Pharmazeutische Technologie

Inhaltsverzeichnis

1. Evolution and design of continuous bioreactors for the production of biologics
2. Continuous countercurrent chromatography for the downstream processing of bioproducts: A focus on flow-through technologies Application of multicolumn countercurrent solvent gradient purification to the polishing of therapeutic proteins
3. Continuous precipitation technologies for the recovery of bioproducts
4. Continuous Recovery and Purification of Bioproducts on the Basis of Adsorption Technology
5. General Platform for Development of Integrated Continuous Downstream Processes
6. Model-based digitalization of biopharmaceutical processes Fill-Finish: large scale manufacturing consideration

Über Autor(innen)

Moscatelli, Davide
Davide Moscatelli received his Laurea cum laude in Chemical Engineering at the Politecnico di Milano in 2002, and his PhD in Chemical Engineering in 2006. He is full professor of Applied Physical Chemistry at Politecnico di Milano and he collaborates with ETH Zurich since 2007.
His main research interests are in the material synthesis for technological applications, with particular emphasis on polymer materials, nanomaterials and chemical compounds for biomedical and oil&gas applications. The general aim of his research is the development of new approaches to synthesize and functionalize innovative, efficient, and tunable smart materials. Davide Moscatelli is co-author of more than 120 papers on international journals and more than 10 patents. H-index: 26. Davide Moscatelli serves as lecturer of Petroleum Technologies and Refining Processes course at Politecnico di Milano. Davide Moscatelli supervised more than 100 Bachelor thesis students in Chemical Engineering, more than 100 Master thesis students in Chemical Engineering and Material Engineering, and more than 10 PhD theses in Industrial Chemistry and Chemical Engineering. He is ViceDirector of the PhD course of Industrial Chemistry and Chemical Engineering at Politecnico di Milano (http://phd.chem.polimi.it/staff/) and, since 2017, he is Member of the Faculty Committee for the strategic plan Polimi2040 at Politecnico di Milano. Davide Moscatelli is a member of the editorial board and advisory panel of several international scientific journals. He is co-founder of Captive Systems srl, a spin-off company of Politecnico di Milano active in use of smart nanomaterials for wastewater treatments.