Prakash / Vangalapati | Studies on Chebulinic Acid Extraction from Terminalia chebula species | E-Book | sack.de
E-Book

E-Book, Englisch, 124 Seiten

Prakash / Vangalapati Studies on Chebulinic Acid Extraction from Terminalia chebula species

Extraction, soxhlet extraction, Modelling, Fermentation, Column Chromatography and Anticancer activity
1. Auflage 2013
ISBN: 978-3-656-49474-4
Verlag: GRIN Publishing
Format: PDF
Kopierschutz: 0 - No protection

Extraction, soxhlet extraction, Modelling, Fermentation, Column Chromatography and Anticancer activity

E-Book, Englisch, 124 Seiten

ISBN: 978-3-656-49474-4
Verlag: GRIN Publishing
Format: PDF
Kopierschutz: 0 - No protection



Master's Thesis from the year 2012 in the subject Engineering - Chemical Engineering, Andhra University (Andhra University College of Engineering (A)), course: M.Tech Bio Technology, language: English, abstract: Herbal drug product has a special place in the world of pharmaceuticals. Terminalia chebula is a deciduous tree, used in traditional medicines. It is reported to contain various bio chemical compounds such as tannins, chebulinic acid, ellagic acid, gallic acid, punicalagin, flavonoids etc. It has been reported as antioxidant, antidiabetic, antibacterial, antiviral, antifungal, anticancerous, antiulcer, antimutagenic, wound healing activities etc. The optimization of physico-chemical parameters like effects of different solvents, soaking time, extraction time with hexane, particle size, different solvent percentages, different volumes of hexane with ethanol and methanol as solvents and pH for the extraction of Total Phenolic Content, Chebulinic acid and Quercetin were studied. The extraction was carried out by employing various organic solvents using Soxhlet extractor method. Ethanol was found to be the best solvent for the extraction of Chebulinic acid from Terminalia chebula species. Soxhlet extractor was carried out using ethanol at different extraction times to verify the mathematical model proposed in this work. The optimization of physico-chemical parameters required for obtaining the highest production of Chebulinic acid using Baker's yeast (Saccharomyces cerevisia.Among the extraction process (Batch, Soxhlet& Fermentation process) the highest Chebulinic acid production was obtained from fermentation process. The partition coefficient for fermentation, soxhlet & batch extraction were found to be 3.83, 2.0 & 0.64. The extraction of Chebulinic acid from Terminalia chebula by Soxhlet extraction and purify the Chebulinic acid by using Column chromatography. Chebulinic acid showed many bioactivities including inhibition of cancer cell growth, inhibiting the contractile responses of cardiovascular muscles, anti-fungal, anti-bacterial activities etc. Finally the Chebulinic acid extraction from Terminalia chebula plays a vital role in medicine, biotechnology and various pharmacological activities.

Dr.Meena Vangalapati M.Tech., Ph.D, Associate Professor, Department of Chemical Engineering, Andhra University College of Engineering (A), Andhra University, Visakhapatnam, Andhra Pradesh, India. She has 13 years of teaching experience and published 60 more Papers published in National and International Reputed Journals, published 7 monographs/Books.
Prakash / Vangalapati Studies on Chebulinic Acid Extraction from Terminalia chebula species jetzt bestellen!

Weitere Infos & Material


Vangalapati, Meena
Dr.Meena Vangalapati M.Tech., Ph.D, Associate Professor, Department of Chemical Engineering, Andhra University College of Engineering (A), Andhra University, Visakhapatnam, Andhra Pradesh, India. She has 13 years of teaching experience and published 60 more Papers published in National and International Reputed Journals, published 7 monographs/Books.



Ihre Fragen, Wünsche oder Anmerkungen
Vorname*
Nachname*
Ihre E-Mail-Adresse*
Kundennr.
Ihre Nachricht*
Lediglich mit * gekennzeichnete Felder sind Pflichtfelder.
Wenn Sie die im Kontaktformular eingegebenen Daten durch Klick auf den nachfolgenden Button übersenden, erklären Sie sich damit einverstanden, dass wir Ihr Angaben für die Beantwortung Ihrer Anfrage verwenden. Selbstverständlich werden Ihre Daten vertraulich behandelt und nicht an Dritte weitergegeben. Sie können der Verwendung Ihrer Daten jederzeit widersprechen. Das Datenhandling bei Sack Fachmedien erklären wir Ihnen in unserer Datenschutzerklärung.