Potter / Melchers / Weigert Oncogenes in B-Cell Neoplasia

Workshop at the National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, March 5–7, 1984
Erscheinungsjahr 2012
ISBN: 978-3-642-69860-6
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 113, 268 Seiten, eBook

Reihe: Current Topics in Microbiology and Immunology

Zielgruppe

Research

Autoren/Hrsg.

Potter, M.

Melchers, F.

Weigert, M.

Inhaltsverzeichnis

Cooperation of Oncogenes in B-Cell Neoplasia.- Introductory Remarks.- Activated Oncogenes in Burkitt’s Lymphoma.- Detection of an Adenovirus E1A-like Activity in Mammalian Cells.- Does the Large T Protein of Polyoma Virus Regulate the Expression of the Celluar myc Gene?.- Genome Structure and Host Range Restriction of the Lymphotropic Papovavirus (LPV): Identification of a Viral Lymphocyte Specific Enhancer Element.- Tlym-I, a Stage Specific Transforming Gene Shares Homology with MHC I Region Genes.- Structural and Functional Analysis of ras and Blym Oncogenes.- Structural Organization of Mouse emyb Locus and the Mechanism of its Rearrangement in ABPL-2 Tumor Line Induced by Pristane and Abelson Murine Leukemia Virus.- Disruption and Activation of the c-myb Locus by M-MuLV Insertion in Plasmacytoid Lymphosarcomas Induced by Pristane and Abelson Viruses.- Follicular Hyperplasia in the Prelymphomatous Avian Bursa, Relationship to the Incidence of B-Cell Lymphomas.- Growth Factors in B-Cell Neoplasia.- Multiple Steps in the Transformation of Normal B Cells Towards Neoplasia.- Transferrin Receptors Regulate Proliferation of Normal and Malignant B Cells.- Cloned Neoplastic B Cells Release a Growth Factor Which Augments Lymphokine-Mediated Proliferation of Normal B Cells.- The Action of an Lyb2.1-Specific Monoclonal Antibody in Soluble or Immobilized Form on Resting and Activated B Cells.- T Cell Factors Regulating B Cell Activation and Differentiation.- Interleukin 3 Dependent Retrovirus Induced Lymphomas: Loss of the Ability to Terminally Differentiate in Response to Differentiation Factors.- Growth Regulation of a B-Cell Lymphoma via the Antigen Receptor.- Interleukin-2 Receptors on Activated Malignant and Normal B-Cells.- Immuno Affinity Purified Interleukin 2 (IL2)Induces B Cell Growth.- Factors Affecting Normal and Malignant B Lymphocyte Precursors.- Immunoglobulin Heavy Chain Switching in Cultured I.29 Murine B Lymphoma Cells: Commitment to an IgA or IgE Switch.- Regulation of myc Gene Expression in Normal and Neoplastic Cells.- The Regulation of c-myc by Growth Signals.- Immune Regulation of the c-myc Oncogene in a Murine B Lymphoma.- The Translocated c-myc Oncogene of Burkitt Lymphoma is Differentially Regulated in Lymphoblastoid vs Plasma Cells.- Mechanism of myc Gene Activation.- Modes of c-myc Oncogene Activation in Murine Plasmacytomas.- DNA Sequences Involved in the Rearrangement and Expression of the Murine c-myc Gene.- Activation of the c-myc Oncogene in B and T Lymphoid Tumors.- The c-myc Gene Paradox in Burkitt’s Lymphoma Chromosomal Translocation.- Amplification, Expression, and Rearrangement of c-myc and N-myc Oncogenes in Human Lung Cancer.- Chromosomal Aberrations in Murine Plasmacytomas.- Chromatin Structural Changes in the Putative Regulatory Region of c-myc Accompany the Translocation in a Burkitt Lymphoma.- Aberrant Rearrangements at the Murine Light Chain Locus in Plasmacytomas.- The myc Gene Product.- myc-Encoded Proteins of Chickens and Men.- Properties of the myc-Gene Product: Nuclear Association, Inhibition of Transcription and Activation in Stimulated Lymphocytes.- In Vitro Culture of B Lymphocytes.- to Long-Term Cultures of Normal B Lymphocytes.- Characteristics of Continuous in vitro Lines of BALB/c and NZB B Cells.- Development of Cells of the B-Lymphocyte Lineage in Longterm Culture.- Coexpression of Lyb-2 and Mac-1by Murine Lymphomas and Subpopulations of Normal Spleen and Bone Marrow Cells.- Ly-1 as a Differentiation Antigen on Normal and Neoplastic B Cells.- Propagation of B Lymphocytes inVitro.- Potential New Systems for the Generation of B Cell Tumors.- Identification of a Transforming Virus from a Lymphoma of a Mouse Infected with a Wild Mouse Retrovirus.- Transformation Capacities of a Murine Retrovirus Encoding an Avian myc Oncogene.- The CH Series of Murine B Cell Lymphomas: Identification of Cross-reactive Idiotypes and Restricted Antigen Specificities.- Interaction of Acute Transforming Retroviruses with Murine Hematopoietic Cells.- Monoclonal Antibody to Abelson Lymphoma Cells.