Poretsky Principles of Diabetes Mellitus

2. Auflage 2010
ISBN: 978-0-387-09841-8
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 852 Seiten

'Principles of Diabetes Mellitus, Second Edition' is an important update to the comprehensive textbook first published in 2002 and reissued in 2004. It is written for physicians of all specialties who, on a daily basis, deal with an illness which has reached epidemic proportions. The book is also intended for medical students and investigators of all aspects of diabetes. The last five years have witnessed major developments in our understanding of diabetes and in therapeutic approaches to this disease. Thus, in addition to updating all chapters, the authors added eight new chapters to the second edition. 'Principles of Diabetes Mellitus, Second Edition' covers diabetes in all of its aspects - genetics, epidemiology, pathophysiology, clinical manifestations, therapy and prevention.

Leonid Poretsky, Chief, Division of Endocrinology and Metabolism, Beth Israel Medical Center, New York. NY. His experience and excellent cadre of chapter authors will offer an authoritative review of diabetes.

Autoren/Hrsg.

Poretsky, Leonid

Inhaltsverzeichnis

1;Preface to the Second Edition;5
2;Preface to the First Edition;6
3;Contents;7
4;Contributors;11
5;Part I;17
5.1;The Main Events in the History of Diabetes Mellitus;18
6;Part II Physiology of Glucose Metabolism;32
6.1;Normal Glucose Homeostasis;33
6.2;Endocrine Pancreas;50
6.3;The Role of Incretins in Insulin Secretion;69
6.4;Cellular Mechanisms of Insulin Action;87
6.5;The Role of Brain in Glucose Metabolism;100
7;Part III Diagnosis and Epidemiology of Diabetes;116
7.1;Diagnostic Criteria and Classification of Diabetes;117
7.2;Epidemiology;126
7.3;Diabetes in Culturally Diverse Populations: From Biology to Culture;137
8;Part IV Genes and Diabetes;153
8.1;Genetics of Type 2 Diabetes: From Candidate Genes to Genome- Wide Association Analysis;154
8.2;Rodent Models of Diabetes;171
9;Part V Diabetes Syndromes;185
9.1;Type 1 Diabetes Mellitus: Epidemiology, Genetics, Pathogenesis, and Clinical Manifestations;186
9.2;Type 2 Diabetes Mellitus: Epidemiology, Genetics, Pathogenesis, and Clinical Manifestations;207
9.3;Maturity-Onset Diabetes of the Young: Molecular Genetics, Clinical Manifestations, and Therapy;225
9.4;Diabetes in Pregnancy;237
9.5;Secondary Causes of Diabetes Mellitus;249
9.6;Syndromes of Extreme Insulin Resistance;263
10;Part VI Complications of Diabetes;282
10.1;Acute Hyperglycemic Syndromes: Diabetic Ketoacidosis and the Hyperosmolar State;283
10.2;Hypoglycemia in Diabetes Mellitus;298
10.3;Intake of Advanced Glycation Endproducts: Role in the Development of Diabetic Complications;314
10.4;Diabetic Retinopathy;332
10.5;Diabetic Nephropathy;348
10.6;Diabetic Neuropathy;357
10.7;Peripheral Vascular Disease in Diabetes;371
10.8;The Diabetic Foot;380
10.9;Male Sexual Dysfunction in Diabetes Mellitus;399
10.10;Gastrointestinal Manifestations of Diabetes;416
10.11;Dyslipidemia: Pathogenesis and Management;432
10.12;Dermatological Complications of Diabetes Mellitus; Allergy to Insulin and Oral Agents;454
11;Part VII Related Disorders;469
11.1;Obesity - Genetics, Pathogenesis, Therapy;470
11.2;Hypertension;484
11.3;Coronary Artery Disease and Cardiomyopathy;494
11.4;Polycystic Ovary Syndrome;509
11.5;Insulin Resistance and the Metabolic Syndrome;525
11.6;Diabetes and Liver Disease;550
11.7;The Increased Risk of Cancer in Obesity and Type 2 Diabetes: Potential Mechanisms;571
11.8;Diabetes and Sleep Disorders;592
11.9;HIV Infection and Diabetes;607
12;Part VIII Therapy of Diabetes Mellitus - General Principles;633
12.1;Glycemic Goals;634
12.2;Behavioral and Educational Approaches to Diabetes Self- Management;648
12.3;Dietary Therapy of Diabetes Mellitus;665
12.4;Exercise in the Therapy of Diabetes Mellitus;675
12.5;Therapy of Type 1 Diabetes Mellitus;697
12.6;Treating Type 2 Diabetes Mellitus;718
12.7;Prevention of Microvascular Complications of Diabetes - General Overview;735
12.8;Psychiatric Care of the Patient with Diabetes;740
12.9;Management of Diabetes and Hyperglycemia in the Hospital Setting;757
12.10;The Future of Diabetes Therapy;771
13;Part IX Diabetes Prevention;785
13.1;Prevention of Type 1 Diabetes Mellitus;786
13.2;Prevention of Type 2 Diabetes Mellitus;804
14;Part X;816
14.1;Resources for Patients with Diabetes;817
15;Subject Index;827