Buch, Englisch, 209 Seiten, Format (B × H): 175 mm x 250 mm, Gewicht: 582 g
Volume 34
Buch, Englisch, 209 Seiten, Format (B × H): 175 mm x 250 mm, Gewicht: 582 g
Reihe: Advances and Technical Standards in Neurosurgery
ISBN: 978-3-211-78740-3
Verlag: Springer Vienna
. 6 Patternsofcelldeath. 8 Autophagy:apotentialTrojanhorseformalignantgliomas. 11 Therapeuticbene?tsoftemozolomide. 13 Localtherapiesforglioblastomas. 15 Ongoingclinicaltrialsforglioblastomas. 16 Growthfactorreceptorinhibitors. 17 PI3K=Akt,mTORandNF- Binhibitors. 17 Matrixmetalloproteinase(MMP)inhibitors(MMPI). 18 Angiogenesistargeting. 19 Cellularandvaccinationtherapies. 20 Genetherapy. 20 Reducingmalignantgliomacellmotilityinordertorestore pro-apoptoticdrugsensitivity. 20 Thesodiumpumpconstitutesapotentialtargettocombat malignantgliomas. 21 Thesodiumpump. 22 Cardiotonicsteroids:ligandsofthesodiumpump. 24 VIII Contents Thesodiumpumpisinvolvedincancercellproliferation, migrationanddeath. 24 Braintumorstemcellsapotentialtargettocombatmalignantgliomas. 26 Conclusions. 27 References. 28 € Deepbrainstimulationforpsychiatricdisorders–stateoftheart. T. E. SCHLA APFER and B. H. BEWERNICK, Brain Stimulation Group, Department of Psychiatry and Psychotherapy,UniversityHospitalBonn,GermanyandDepartmentsofPsychiatry andMentalHealth,TheJohnsHopkinsUniversity,MD,USA Abstract. 37 Introduction. 38 Historyofdeepbrainstimulation. 39 PrinciplesofDBS. 40 NeurobiologyofdepressionandOCD. 41 Neurobiologyofdepression. 41 NeurobiologyofOCD. 42 StudiesofDBSandpsychiatricdisorders. 43 Problemsintargetselection. 43 Targetsindepression. 43 TargetsinOCD. 46 SafetyandadvantagesofDBS. 47 EthicalaspectsandstandardsinDBS. 51 Ethicalconsiderations. 51 ThepathtowardsmandatorystandardsforDBSinpsychiatricdisorders. 52 Conclusions. 53 ThefutureofDBS. 54 References. 54 Standards High?owextracranialtointracranialvascularbypassprocedureforgiantan- rysms:indications,surgicaltechnique,complicationsandoutcome. H. C. PATEL and P. J. KIRKPATRICK, Department of Academic Neurosurgery, Addenbrooke’s Hospital,UniversityofCambridge,Cambridge,UK Abstract. 61 Introduction. 62 Surgicaltechnique. 67 Cranialexposure. 69 Cervicalexposure. 70 Saphenousveinexposure. 71 Preauriculartunnel. 72 Contents IX Anastamoses. 73 Distalanastamosis. 73 Externalcarotidanastamosis. 74 Closureandpostoperativecare. 77 Discussion. 77 Comparisonofoutcomes. 77 Choosingthetypeofgraft. 78 Longtermpatencyofgrafts. 79 Ischaemiccomplications. 79 Anticoagulationrelatedmorbidity. 81 Conclusion.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Chirurgie Neurochirurgie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Bildgebende Verfahren, Nuklearmedizin, Strahlentherapie Neuroradiologie
Weitere Infos & Material
Advances.- Present and potential future adjuvant issues in high-grade astrocytic glioma treatment.- Deep brain stimulation for psychiatric disorders — state of the art.- Standards.- High flow extracranial to intracranial vascular bypass procedure for giant aneurysms: indications, surgical technique, complications and outcome.- Decompression for Chiari type I-malformation (with or without syringomyelia) by extreme lateral foramen magnum opening and expansile duraplasty with arachnoid preservation: comparison with other technical modalities (Literature review).- Vagal nerve stimulation — a 15-year survey of an established treatment modality in epilepsy surgery.- Surgical anatomy and surgical approaches to the lateral ventricles.
