Buch, Englisch, 188 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 471 g
Buch, Englisch, 188 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 471 g
Reihe: Biology of Extracellular Matrix
ISBN: 978-3-642-16832-1
Verlag: Springer
Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions.
This volume of the series “Biology of Extracellular Matrix” reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Biowissenschaften Mikrobiologie
- Naturwissenschaften Biowissenschaften Zellbiologie
- Naturwissenschaften Biowissenschaften Kohlenhydrate
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
Weitere Infos & Material
Heparan Sulfate Proteoglycan in Inflammation and Angiogenesis.- Heparan Sulfate Proteoglycans in Infection.- Glycans in cancer.- Glycosaminoglycans in atherosclerosis and thrombosis.- Glycans in Embryonic Stem Cells.- Heparan sulfate proteoglycans in cancer progression and therapy.- Structure and biological activities of glycosaminoglycan analogs from marine invertebrates: new therapeutic agents?.