Paoletti / Kritchevsky Advances in Lipid Research

1. Auflage 2014
ISBN: 978-1-4832-1540-2
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band Volume 18, 332 Seiten, Web PDF

Reihe: Advances in Lipid Research

Advances in Lipid Research, Volume 18 is a seven-chapter text that brings together significant research studies on atherosclerosis. The opening chapter describes the pathological techniques in atherosclerosis research. The succeeding chapters deal with the influence of lipid-lowering drugs on bile acid metabolism and the cholesterol metabolism in ovarian tissue. Other chapters examine the principal role of sulfolipids and the influence of dietary linoleic acids on blood pressure regulation in rats. The closing chapters review the influence of nonnutritive fiber on lipid metabolism and the influence of fiber on lipid-associated diseases. These chapters also consider the techniques for polar lipid analysis. This book will be of great value to lipid chemists, biochemists, and researchers.

Autoren/Hrsg.

Paoletti, Rodolfo

Kritchevsky, David

Inhaltsverzeichnis

1;Front Cover;1
2;Advances in Lipid Research;4
3;Copyright Page;5
4;Table of Contents;6
5;LIST OF CONTRIBUTORS;10
6;PREFACE;12
7;Chapter 1. Techniques in Pathology in Atherosclerosis Research;14
7.1;I. Introduction;14
7.2;II. Methods of Induction of Atherosclerosis;17
7.3;III. Diagnosis of Atherosclerosis and Assessment of Lesions;29
7.4;IV. Epidemiology;54
7.5;V. Tissue Culture;57
7.6;VI. Statistical Evaluation of Morphometric Results;60
7.7;VII. Summary;61
7.8;References;62
8;Chapter 2. Effects of Hypolipidemic Drugs on Bile Acid Metabolism in Man;78
8.1;I. Introduction;78
8.2;II. Absorbable Hypolipidemic Agents;79
8.3;III. Nonabsorbable Hypolipidemic Agents;89
8.4;References;109
9;Chapter 3. Cholesterol Metabolism by Ovarian Tissue;116
9.1;I. Introduction;116
9.2;II. Where Does Ovarian Cholesterol Come From?;117
9.3;III. Lipoprotein Metabolism by Ovarian Cells;125
9.4;IV. Ovarian Cholesteryl Ester Metabolism;133
9.5;V. Cholesterol Side Chain Cleavage;142
9.6;VI. Do the Ovaries Secrete Cholesterol?;156
9.7;VII. Compartmentalization of Ovarian Sterol Metabolism and Intracellular Sterol Transport;157
9.8;VIII. A Model of the Regulation of Cholesterol Metabolism in the Rat Corpus Luteum;160
9.9;References;166
10;Chapter 4. Metabolism of Sulfolipids in Mammalian Tissues;176
10.1;I. Introduction;176
10.2;II. Classification, Occurrence, and Turnover;177
10.3;III. Biosynthesis of Sulfolipids;184
10.4;IV. Desulfation of Sulfolipids;194
10.5;V. Immunological Properties of Sulfolipids;204
10.6;VI. Inherited Disorders of Sulfolipid Metabolism;205
10.7;VII. Role of Sulfolipids in Mammalian Metabolism;209
10.8;VIII. Summary and Conclusions;211
10.9;References;213
11;Chapter 5. Influence of Dietary Linoleic Acid Content on Blood Pressure Regulation in Salt-Loaded Rats (with Special Reference to the Prostaglandin System);220
11.1;I. Introduction;220
11.2;II. Dependence of Blood Pressure on Dietary Linoleic Acid;222
11.3;III. Significance of Dietary Sodium Chloride;223
11.4;IV. Body Weight;223
11.5;V. Fatty Acid Pattern in Tissue Lipids;224
11.6;VI. Prostaglandin Metabolism;224
11.7;VII. Influence on Blood Pressure of Prostaglandin Biosynthesis Inhibitors;230
11.8;VIII. Sympathetic Nervous System;233
11.9;IX. Kidney Function;235
11.10;X. Vessel Reactivity;237
11.11;XI. Conclusions;239
11.12;References;241
12;Chapter 6. The Role of Dietary Fiber in Lipid Metabolism;246
12.1;I. Introduction;246
12.2;II. Definition and Analysis;247
12.3;III. Interactions in Lipid Metabolism;247
12.4;IV. Involvement in Lipid-Associated Diseases;250
12.5;V. Conclusions;259
12.6;References;260
13;Chapter 7. Current Techniques of Extraction, Purification, and Preliminary Fractionation of Polar Lipids of Natural Origin;264
13.1;I. Introduction;264
13.2;II. Extraction of Lipids from Biological Material;265
13.3;III. Purification of Extracted Lipids from Nonlipid Contaminants;276
13.4;IV. Preliminary Fractionation of Total Polar Lipids;283
13.5;V. Conclusion;294
13.6;VI. Summary;296
13.7;References;296
14;AUTHOR INDEX;300
15;SUBJECT INDEX;330
16;CONTENTS OF PREVIOUS VOLUMES;334