Opioids II

1993
ISBN: 978-3-642-77540-6
Verlag: Springer
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, Band 104 / 2, 840 Seiten, eBook

Reihe: Handbook of Experimental Pharmacology

This two-volume book provides the first comprehensive survey of opioid research, a field which has accumulated a tremendous amount of literature since the identification of opioid receptors and their endogenous ligands. In more than 60 chapters experts present state-of-the-art reviews of this fascinating field, the topics ranging from molecular biology to clinical applications. Part I covers the multiplicity of opioid receptors, the chemistry of opiates and opioid peptides as well as the neurophysiology of opioids. Part II reviews a broad spectrum of physiological and behavioral functions and pharmacological actions of opioids, together with their neuroendocrinology, opioid tolerance and dependence, concluding with pathophysiological aspects and clinical use.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Weitere Mitwirkende

Adler, M.W.

Almeida, O.F.X.

Bailey, P.L.

Bertalmio, A.J.

Bicknell, R.J.

Bryant, H.U.

Burks, T.F.

Castellano, C.

Cella, S.G.

Comitini, G.

Cooper, S.J.

Cowan, A.

Faden, A.I.

Fields, H.L.

Florez, J.

Foley, K.M.

France, C.P.

Geller, E.B.

Genazzani, A.R.

Grossman, A.B.

Han, J.-S.

Holaday, J.W.

Hurle, A.

Introini-Collison, I.B.

Kilpatrick, D.L.

Kirkham, T.C.

Kromer, W.

Locatelli, V.

McGaugh, J.L.

McLoughlin, L.

Medbak, S.

Millan, M.J.

Müller, E.E.

Naber, D.

Nyberg, F.

O'Brien, C.P.

Petraglia, F.

Porreca, F.

Przewlocki, R.

Schulz, R.

Schwarz-Stevens, K.

Shippenberg, T.S.

Stein, C.

Tortella, F.C.

Way, E.L.

Winger, G.

Woods, J.H.

Yaksh, T.L.

Inhaltsverzeichnis

Section E: Pharmacology and Behavior.- 31 Brainstem Mechanisms of Pain Modulation: Anatomy and Physiology.- 32 Supraspinal Opioid Receptors in Antinociception.- 33 The Spinal Actions of Opioids.- 34 Peripheral Mechanisms of Opioid Analgesia.- 35 Acupuncture and Stimulation Produced Analgesia.- 36 Multiple Opioid Systems and Chronic Pain.- 37 Gastrointestinal Effects of Opioids.- 38 Role of Endogenous Opioids in Central Cardiovascular Regulation and Dysregulation.- 39 Physiological Functions of Opioids: Temperature Regulation.- 40 Opioid Mechanisms in the Control of Food Consumption and Taste Preferences.- 41 Opioids in Respiration and Vomiting.- 42 Opioid Systems and Stress.- 43 Role of Endogenous Opioid and Opioid Receptors in Central Nervous System Injury.- 44 Opioids: Epilepsy and Neuroprotection.- 45 Opioids in Immunologic Processes.- 46 Effect of Opioids on the Spontaneous Behavior of Animals.- 47 Involvement of Opioid Peptides in Learning and Memory.- 48 Establishing Correlations Between the Pharmacodynamic Characteristics of Opioid Agonists and Their Behavioral Effects.- Section F: Neuroendocrinology.- 49 Opioid Peptides in the Regulation of Anterior Pituitary Hormones.- 50 Opioids and the Neuroendocrine Control of Reproduction.- 51 Opioids in the Neurohypophysial System.- 52 Opioids Peptide Expression in Peripheral Tissues and Its Functional Implications.- Section G: Reinforcement - Tolerance/Dependence.- 53 Opioid Tolerance and Physical Dependence and Their Relationship.- 54 Opioid Tolerance/Dependence in Isolated Organs.- 55 Opioid Abuse Liability Assessment in Rhesus Monkeys.- 56 Motivational Effects of Opioids.- Section H: Clinical Aspects.- 57 CSF Opioids in Pathophysiology.- 58 Circulating Opioids in Man.- 59 Opioid Analgesics in Clinical Pain Management.- 60 Opioids in Operative Anesthesia.- 61 ?-Endorphin in Human Reproduction.- 62 Opioids in the Etiology and Treatment of Psychiatric Disorders.- 63 Opioid Addiction.