Regenerative Engineering of Musculoskeletal Tissues and Interfaces

Erscheinungsjahr 2015
ISBN: 978-1-78242-301-0
Verlag: Elsevier Science

Buch, Englisch, 462 Seiten, Format (B × H): 154 mm x 238 mm, Gewicht: 867 g

Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces.

Autoren/Hrsg.

Nukavarapu, Syam

Freeman, Joseph

Laurencin, Cato

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Medizinische Biotechnologie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe

Inhaltsverzeichnis

Part One: Basic Elements of Musculoskeletal Tissue Engineering

1. Biomaterials and Scaffolds for musculoskeletal tissue engineering

2. Cells for musculoskeletal tissue engineering

3. Growth Factors for musculoskeletal tissue engineering

4. Mechanical Forces in musculoskeletal tissue engineering

Part Two: Individual Musculoskeletal Tissues

5. Bone tissue engineering

6. Cartilage tissue engineering

7. Ligament tissue engineering

8. Tendon tissue engineering

9. Meniscus tissue engineering

10. Muscle tissue engineering

11. Vascularization of engineered musculoskeletal tissues

12. Neural Innervation of engineered musculoskeletal tissues

Part Three: Musculoskeletal Tissue Interfaces

13. Bone-Cartilage interface

14. Bone-Tendon interface

15. Bone-Ligament interface

16. Bone-Meniscus interface

17. Muscle-Tendon interface

Über Autor(innen)

Freeman, Joseph
Joseph W. Freeman is Associate Professor in the Department of Biomedical Engineering at Rutgers University his research interests
include new biomaterial-based strategies for the regeneration of musculoskeletal tissues.

Nukavarapu, Syam
Dr. Nukavarapu is an Assistant Professor in the Department of Orthopedic Surgery at the University of Connecticut Health Center (UConn Health), Connecticut. He has joint appointments with the departments of Biomedical Engineering (BME) and Materials Science & Engineering (MSE) at The University of Connecticut. His research interests include Biomaterials, Stem Cells, and Tissue Engineering. Dr. Nukavarapu's laboratory has been focused on developing advanced matrix systems for Bone and Osteochondral Tissue Engineering. His group is at the forefront of developing Completely Intra-operative Tissue Engineering Strategies (CITES) for on-site therapy or bedside tissue engineering. Dr. Nukavarapu has published about 50 articles in peer-reviewed journals and has 10 book chapters and holds 2 patents. He is serving as editorial board member for many field journals. Dr. Nukavarapu teaches Advanced Biomaterials (BME 4701) course at the University of Connecticut.