Buch, Englisch, 219 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 359 g
Buch, Englisch, 219 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 359 g
Reihe: Basic Science for the Cardiologist
ISBN: 978-1-4899-9429-5
Verlag: Springer US
Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has role in the pathogenesis of arteriosclerosis.
Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Biochemistry of Adrenomedullin.- Adrenomedullin Receptor and Signal Transduction.- Adrenomedullin Gene.- Adrenomedullin Expression and Secretion.- Biological Action of Adrenomedullin.- Circulating Adrenomedullin.- Role of Adrenomedullin in Cardiovascular Diseases.- Adrenomedullin as an Adipokine.- Adrenomedullin Knockout Mouse and Transgenic Mouse.- Pleiotropic Effect of Adrenomedullin: Lessons from Pure Adrenomedullin Knockout Mouse.- Therapeutic Application of Adrenomedullin.- Therapeutic Potentials of Adrenomedullin for Heart Failure and Pulmonary Hypertension.
