An Introduction to Population Genetics

Theory and Applications
1. Auflage 2013
ISBN: 978-1-60535-153-7
Verlag: Sinauer Associates

Buch, Englisch, 298 Seiten, Book, Format (B × H): 235 mm x 178 mm

This book covers both classical population genetics theory developed in terms of allele and haplotype frequencies and modern population genetics theory developed in terms of coalescent theory. It features applications of theory to problems that arise in the study of human and other populations and assumes little prior knowledge of mathematics.

Zielgruppe

Lower undergraduate

Autoren/Hrsg.

Nielsen, Rasmus

Slatkin, Montgomery

Inhaltsverzeichnis

Preface.- Introduction.- 1. Allele Frequencies, Genotype Frequencies, and Hardy–Weinberg Equilibrium.- 2. Genetic Drift and Mutation.- 3. Coalescence Theory: Relating Theory to Data.- 4. Population Subdivision.- 5. Inferring Population History and Demography.- 6. Linkage Disequilibrium and Gene Mapping.- 7. Selection I.- 8. Selection in a Finite Population.- 9. The Neutral Theory and Tests of Neutrality.- 10. Selection II: Interaction and Conflict.- 11. Quantitative Genetics.- Appendix A. Basic Probability Theory.- Appendix B. The Exponential Distribution and Coalescence Times.- Appendix C. Maximum Likelihood and Bayesian Estimation.- Appendix D. Critical Values of the Chi-square Distribution with d Degrees of Freedom.- Answers to Exercises.- Glossary.

Über Autor(innen)

Rasmus Nielsen, University of California, Berkeley, USA. Montgomery Slatkin, University of California, Berkeley, USA.