Structure and Function in Cell Signalling

1. Auflage 2008
ISBN: 978-0-470-02551-2
Verlag: WILEY

Buch, Englisch, 410 Seiten, Format (B × H): 170 mm x 244 mm, Gewicht: 881 g

Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities - the 'nuts and bolts' of cellular information exchange.

With an emphasis on clarity of presentation throughout, the book teaches the basic principles focusing on a mature core of knowledge, providing students with a foundation of learning in this complex and potentially confusing subject. It also addresses the issue of variation in the numbering of key amino acids as well as featuring interaction with RasMol software, and exercises to aid understanding.

Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities - the 'nuts and bolts' of cellular information exchange.

* An accessible introduction to the complex field of cell signalling.

* Interacts with RasMol software - freely downloadable for viewing structures in 3D.

* Includes exercises and clear instructions in the use of RasMol.

* Well illustrated in full colour throughout.

Structure and Function in Cell Signalling will prove invaluable to students across a range of life science degree programmes including biochemistry, cell and molecular biology, physiology, biomedicine and oncology. This book will provide a clear, accessible introduction to this rapidly expanding field.

Autoren/Hrsg.

Nelson, John

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie
• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

Acknowledgments

Preface

1 The components and foundations of signalling

References

2 Enzymes and receptors - quantitative aspects

References

3 Modules and motifs in transduction

References

4 Protein kinase enzymes - activation and auto-inhibition

References

5 7-pass receptors and the catabolic response

References

6 Single pass growth factor receptors

References

7 G proteins (I) - monomeric G proteins

References

8 G proteins (II) - heterotrimeric G proteins

References

9 The insulin receptor and the anabolic response

References

10 Mitogens and cell cycle progression

References

Appendix 1: Worked examples

Appendix 2: RasMol: installation and use

Index