Molecular Evolution and Phylogenetics

Erscheinungsjahr 2000
ISBN: 978-0-19-513585-5
Verlag: Oxford University Press, USA

Buch, Englisch, 352 Seiten, Format (B × H): 178 mm x 254 mm, Gewicht: 663 g

This book presents the statistical methods that are useful in the study of molecular evolution and illustrates how to use them in actual data analysis. Molecular evolution has been developing at a great pace over the past decade or so, driven by the huge increase in genetic sequence data from many organisms, the improvement of high-speed microcomputers, and the development of several new methods for phylogenetic analysis. This book for graduate students and researchers, assuming a basic knowledge of evolution, molecular biology, and elementary statistics, should make it possible for many investigators to incorporate refined statistical analysis of large-scale data in their own work. Nei is one of the leading workers in this area. He and Kumar have developed a computer program called MEGA, which has been sold for about $20 to over 1900 users. For the book, the authors are thoroughly revising MEGA and will make it available via FTP. The book also included analysis using the other most popular programs for phylogenetic studies, including PAUP, PHYLIP, MOLPHY, and PAML.

Autoren/Hrsg.

Nei, Masatoshi

Kumar, Sudhir

Fachgebiete

• Mathematik | Informatik Mathematik Stochastik Wahrscheinlichkeitsrechnung
• Naturwissenschaften Biowissenschaften Angewandte Biologie Biomathematik
• Naturwissenschaften Biowissenschaften Proteinforschung
• Naturwissenschaften Biowissenschaften Biowissenschaften Evolutionsbiologie
• Naturwissenschaften Biowissenschaften Molekularbiologie
• Mathematik | Informatik Mathematik Stochastik Mathematische Statistik
• Naturwissenschaften Biowissenschaften Biowissenschaften Genetik und Genomik (nichtmedizinisch)
• Naturwissenschaften Biowissenschaften Botanik Pflanzenreproduktion, Verbreitung, Genetik
• Naturwissenschaften Biowissenschaften Tierkunde / Zoologie Tiergenetik, Reproduktion

Inhaltsverzeichnis

- 1: Molecular basis of evolution

- 2: Evolutionary changes of amino acid sequences

- 3: Evolutionary changes of DNA sequences

- 4: Synonymous and Nonsynonymous nucleotide subsitutions

- 5: Phylogenetic Trees

- 6: Phylogenetic inference: Distance methods

- 7: Phylogenetic inference: Maximum parsimony methods

- 8: Phylogenetic inference: Maximum likelihood methods

- 9: Accuracies and statistical tests of phylogenetic trees

- 10: Molecular clocks and linearized trees

- 11: Ancestral Nucleotide and amino acid sequences

- 12: Genetic polymorphism and evolution

- 13: Population trees from genetic markers

- 14: Perspectives

- Appendices

- A. Mathematical symbols and notations

- B. Geological timescale

- C. Geological events in the Cenozoic and Mesozoic eras

- D. Evolution of organisms based on the fossil record