Engineering Genetic Circuits

1. Auflage 2009
ISBN: 978-1-4200-8324-8
Verlag: Chapman and Hall/CRC

Buch, Englisch, 306 Seiten, Format (B × H): 161 mm x 240 mm, Gewicht: 628 g

Reihe: Chapman & Hall/CRC Computational Biology Series

An Introduction to Systems Bioengineering
Takes a Clear and Systematic Engineering Approach to Systems Biology

Focusing on genetic regulatory networks, Engineering Genetic Circuits presents the modeling, analysis, and design methods for systems biology. It discusses how to examine experimental data to learn about mathematical models, develop efficient abstraction and simulation methods to analyze these models, and use analytical methods to guide the design of new circuits.

After reviewing the basic molecular biology and biochemistry principles needed to understand genetic circuits, the book describes modern experimental techniques and methods for discovering genetic circuit models from the data generated by experiments. The next four chapters present state-of-the-art methods for analyzing these genetic circuit models. The final chapter explores how researchers are beginning to use analytical methods to design synthetic genetic circuits.

This text clearly shows how the success of systems biology depends on collaborations between engineers and biologists. From biomolecular observations to mathematical models to circuit design, it provides essential information on genetic circuits and engineering techniques that can be used to study biological systems.

Zielgruppe

Undergraduate

Autoren/Hrsg.

Myers, Chris J.

Fachgebiete

• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe

Inhaltsverzeichnis

An Engineer’s Guide to Genetic Circuits. Learning Models. Differential Equation Analysis. Stochastic Analysis. Reaction-Based Abstraction. Logical Abstraction. Genetic Circuit Design. Solutions to Selected Problems. References. Glossary. Index.

Über Autor(innen)

Chris J. Myers is a professor in the Department of Electrical and Computer Engineering at the University of Utah. A co-inventor on four patents and author of more than 80 technical papers and the textbook Asynchronous Circuit Design, Dr. Myers received an NSF Fellowship in 1991 and an NSF CAREER award in 1996. His research interests include formal verification, asynchronous circuit design, and the analysis and design of genetic regulatory circuits.