Harpers Illustrated Biochemistry

29 International ed
ISBN: 978-0-07-179277-6
Verlag: McGraw-Hill Education - Europe

Buch, Englisch, 0 Seiten, Format (B × H): 220 mm x 284 mm, Gewicht: 1646 g

Gain a thorough understanding of the principles of biochemistry and molecular biology as they relate to modern medicineIncludes 16 case historiesClear, concise, and in full color, Harper’s Illustrated Biochemistry is unrivaled in its ability to clarify the link between biochemistry and the molecular basis of disease. Combining outstanding full-color illustrations with integrated coverage of biochemical diseases and clinical information, Harper’s offers an organization and careful balance of detail and brevity not found in any other text on the subject. Following two introductory chapters, the text is divided into six main sections:

Section I addresses the structures and functions of proteins and enzymes.

Section II explains how various cellular reactions utilize or release energy and traces the pathways by which carbohydrates and lipids are synthesized and degraded.

Section III covers the amino acids, their metabolic fates, certain features of protein catabolism, and the biochemistry of the porphyrins and bile pigments.
Section IV describes the structure and function of nucleotides and nucleic acids, DNA replication and repair, RNA synthesis and modification, protein synthesis, the principles of recombinant DNA technology, and new understanding of how gene expression is regulated. Section V deals with aspects of extracellular and intracellular communication.

Section VI includes fifteen special topics, ranging from nutrition, digestion and absorption to the biochemistry of agingNew to this edition: - New chapters on Aging, Cancer, and Clinical Chemistry - Every chapter has been updated to reflect the latest advances in knowledge and technology - Each chapter now begins with a statement of objectives, followed by a brief discussion of the biomedical importance of topics discussed within the chapter - 250 multiple-choice questions to test your knowledge and comprehension - Increased number of tables that encapsulate important information, such as vitamin and mineral requirements

Autoren/Hrsg.

Murray, Robert K.

Murray, Robert

Bender, David

Botham, Kathleen M.

Botham, Kathleen

Kennelly, Peter J.

Kennelly, Peter

Rodwell, Victor W.

Rodwell, Victor

Weil, P. Anthony

Fachgebiete

• Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)

Inhaltsverzeichnis

Section 1: Structures and Functions of Proteins and Enzymes
1. Biochemistry & Medicine2. Water & pH 73. Amino Acids & Peptides4. Proteins:Determination of Primary Structure5. Proteins: Higher Orders of Structure6. Proteins: Myoglobin & hemoglobin7. Enzymes:Mechanism of Action8. Emzymes: Kinetics9. Enzumes: regulation of Activities10. Bioinformatics & Computational BiologySection 2: Bioenergetics and the Metabolism of Carbohydrates and Lipids
11. Bioenergetics: The Role of ATP12. Biologic Oxidation14. Carbohydrates of Physiologic Significance15. Lipds of Physiologic Significance16. Overview of Metabolism & the Provision of Metabolic Fuels17. The Citric Acid Cycle: The Catabolism of Acetyl-CoA18. Glycolysis & the Oxidation of Pyruvate19. Metabolism of Glycogen20. Gluconeogenesis & the Control of Blood Glucose21. The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism22. Oxidation of Fatty Acids: Ketogenesis23. Biosynthesis of Fatty Acids & Eicosanoids24. Metabolism of Acylglycerols & Sphingolipids25. Lipid Transport & Storage26. Cholesterol Synthesis, Transport, & ExcretionSection 3: Metabolism of Proteins and Amino Acids
27. Biosynthesis of the Nutritionally Nonessential Amino Acids28. Catabolism of Proteins & of Amino Acid Nitrogen29. Catabolism of te Carbon Skeletons of Amino Acids30. Conversion of Amino Acids to Speicalized Products31. Pophyrins & Bile PigmentsSection 4: Structure, Function and Replication of Infomraitonal Macromolecules
32. Nucleotides33. Metabolism of Purine & Pyrimidine Nucleotides34. Nucleic Acid Structure & Function35. DNA Organization, Replication, & Repair36. RNA Synthesis, Processing, & Modification37. Protein Synthesis & The Genetic Code38. Regulation of Gene Expression39. Molecular Genetics, Recombinant DNA, & Genomic TechnologySection 5: Biochemistry of Extracellular and Intracullular Communication
40. Membranes: Structure & Function41. The diversity of the Endocrine System42. Hormone Action & Signal TransductionSection 6: Special Topics (will highlight the 16 cases)
43. Nuturition, Digestion & Absorption44. Micronutrients: Vitamins & Minerals45. Free Radicals and Antioxidant Nutrients46. Intracellular Traffic & Sorting of Proteins47. Glycoproteins48. The Extracellular Matrix49. Muscle & the Cytoskeleton50. Plasma Proteins & Immunoglobulins51. Hemostasis & Thrombosis52. Red & White Blood Cells53. Metabolism of Xenobiotics54. The Biochemistry of Aging55. Cancer: An Overview56. Clinical Biochemistry57. Biochemical Case Histories Appendix The Answer Bank Index

Über Autor(innen)

Murray, Robert
McGraw-Hill authors represent the leading experts in their fields and are dedicated to improving the lives, careers, and interests of readers worldwide

Rodwell, Victor
Robert K. Murray, MD, PhD
Professor (Emeritus) of Biochemistry
University of Toronto
Toronto, Ontario Daryl K. Granner, MD
Joe C. Davis Professor of Biomedical Science
Director, Vanderbilt Diabetes Center
Professor of Molecular Physiology and Biophysics and of Medicine
Vanderbilt University
Nashville, Tennessee Peter A. Mayes, PhD, DSc
Emeritus Professor of Veterinary Biochemistry
Royal Veterinary College
University of London
London Victor W. Rodwell, PhD
Professor of Biochemistry
Purdue University
West Lafayette, Indiana