Inflammatory Processes:

Molecular Mechanisms and Therapeutic Opportunities
Softcover Nachdruck of the original 1. Auflage 2000
ISBN: 978-3-0348-9580-4
Verlag: Birkhäuser Basel

Buch, Englisch, 144 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 254 g

Reihe: Progress in Inflammation Research

In November 1998 many of the key leaders of new drug discovery for
inflammatory diseases gathered at Hershey, Pennsylvania for the 9th
International Conference of the Inflammation Research Association. The
Conference was held over a five day period and provided a stimulating
environment for the open exchange of important advances in basic
inflammation research as well as new drug discovery and development.
This book encompasses some of the highlights of several presentations
made at the Conference. It contains some of the latest and important
developments in the field of inflammation research.
Topics include the status of eotaxin and chemokines in asthma and
allergy, signal transduction and regulation of diverse mediators such as
the JNK group of MAP kinases, TNF and IL-1 signaling of NF-kB as well as
regulators of AP-1, macrophage metalloproteinases, lymphotoxin and
further insights into the role of MCP-1 in disease. Also discussed are
drug targets in rheumatoid and osteoarthritis, fibrotic diseases,.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Morgan, Douglas W.

Letts, L. Gordon

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Allergologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

The role of eotaxin and related CC-chemokines in asthma and allergy.- Signal transduction by the JNK group of MAP kinases.- Cellular signaling to NF-?B: Role in inflammation and therapeutic promise.- Small molecule regulators of AP-1 and NF-?B.- Mammalian target of rapamycin: Immunosuppressive drugs offer new insights into cell growth regulation.- Constitutive expression of a tumor suppressor leads to tumor regression in a xenograft model.- Macrophage metalloproteinases in destructive inflammatory diseases.- Lymphotoxin in inflammation and lymphoid organ development: Variations on a theme.- Chemokine/cytokine biology during the evolution of fibrotic disease.- The role of MCP-1 in disease.- The role of chemokines in allergic diseases of the airways.- Ninth International Conference of the Inflammation Research Association, November 1-5, 1998: Summaries of workshops and poster discussions.- Targets in rheumatoid and osteoarthritis.- Signal transduction and regulation of gene expression.- Mediators of inflammation and their enzymes.- Cell adhesion molecules and leukocyte trafficking.- Pulmonary inflammation, fibrosis, and disease.- Angiogenesis, wound repair and skin inflammation.