Mogessie Cellular Architecture and Dynamics in Female Meiosis

Erscheinungsjahr 2025
ISBN: 978-3-031-97173-0
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 226 Seiten

Reihe: Biomedical and Life Sciences

This book brings together a diverse and exciting group of emerging and leading experts in female meiosis, each contributing a chapter that summarizes seminal recent progresses in their area of specialty. With various meiosis topics ranging from cytoskeletal function in worms to studies of oocyte meiosis in large mammals, this collection is intended for fundamental cell biologists interested the basic mechanisms of cell division and differentiation.

Zielgruppe

Research

Autoren/Hrsg.

Mogessie, Binyam

Inhaltsverzeichnis

Cytoskeletal organization and dynamics in female meiosis and early  embryogenesis structure and dynamics in mammalian oocytes.- Conserved functions of Mos-MAPK in oocyte meiosis.- What are the fitness costs of centromere drive?.- Cell cycle regulation of vertebrate female meiotic divisions.- Preserving genomic integrity during female meiosis: Detecting, repairing, and responding to maternal DNA damage.- Canonical and non-canonical roles of the nucleolus in relation to nucleolar function in oocyte meiosis.- Breaking trends: large animal models to study spindle assembly and chromosome segregation in human oocytes.- Aurora kinases: a summary of mouse genetic models used to distinguish their roles in oocyte meiosis and female fertility.- Meiotic spindle organization and function in Drosophila female oocytes.

Über Autor(innen)

Binyam Mogessie studied Biochemistry and Cell Biology as an undergraduate at Jacobs University Bremen, Germany, and earned his Ph.D. in Cell Biology from the Institute of Cancer Research, University of London. He conducted postdoctoral research at the MRC Laboratory of Molecular Biology in Cambridge and the Max Planck Institute in Göttingen, where he discovered novel functions of F-actin in chromosome segregation. In 2019, he established his independent research group at the University of Bristol as a Wellcome Trust and Royal Society Sir Henry Dale Fellow and HFSP Young Investigator. In 2022, he joined Yale University as an Assistant Professor of Molecular, Cellular and Developmental Biology & OBGYN. His lab investigates cytoskeletal organization and chromosome segregation mechanisms in mammalian oocytes, advancing fundamental understanding of female reproductive cell biology.