Merchant | Pharmacological Regulation of Gene Expression in the CNS Towards an Understanding of Basal Ganglial Functions (1996) | Buch | 978-1-138-10574-4 | sack.de

Buch, Englisch, 224 Seiten, Format (B × H): 156 mm x 234 mm, Gewicht: 454 g

Reihe: CRC Press Revivals

Merchant

Pharmacological Regulation of Gene Expression in the CNS Towards an Understanding of Basal Ganglial Functions (1996)


Buch, Englisch, 224 Seiten, Format (B × H): 156 mm x 234 mm, Gewicht: 454 g

Reihe: CRC Press Revivals

ISBN: 978-1-138-10574-4
Verlag: Taylor & Francis Ltd

This book focuses on dopamine-mediated regulation of gene expression within the striatum and associated regions of the central nervous system. It is an excellent review of experimental data on interactions between neuronal systems at systemic, cellular, and molecular levels. Each of the chapters, written by the world's leading scientists, provides an understanding of anatomy, neurochemistry, and cellular and molecular effects. Such an understanding sheds light on the pathophysiology of central disorders involving the basal ganglia and leads to new approaches for the treatment of diseases such as Parkinson's disease and schizophrenia, and also addictions to psychostimulants such as cocaine and amphetamines.
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Professional

Autoren/Hrsg.

Merchant, Kalpana

Fachgebiete

Weitere Infos & Material

Dopamine Mediated Gene Expression in the Neostriatum. D1 and D2 Dopamine Receptor Mediated Gene Regulation in the Striatum. Acute and Long-Term Alteration in Immediate-Early Gene Expression by Antipsychotic Drugs: Downstream Genomic Targets, Behavioral Correlates, and Role of D2, D3, and D4 Receptors. Dopamine Receptor Function: An Analysis Utilizing Antisense Knockout In Vivo. Neurotransmitter Interactions Regulating Striatal Gene Expression. Glutamatergic and Cholinergic Regulation of Immediate Early Gene and Neuropeptide Expression in the Striatum. Molecular Mechanisms of Striatal Gene Regulation: A Critical Role for Glutamate in Dopamine-Mediated Gene Induction. Persistent Alterations in Gene Expression Involved in Behavioral Adaptations. Striatal Gene Expression Involved in Adaptive Responses to Levodopa in Parkinsonian Models: Relevance to Long-Term Clinical Effects of Levodopa Therapy. Plasticity of GAD Expression in Animal Models of Movement Disorders. Pharmacological and Molecular Regulation of the Expression of Dopamine Receptors.

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